孟鲁司特钠联合妥洛特罗贴治疗慢性咳嗽患儿效果及对血清IgE水平影响.docVIP

孟鲁司特钠联合妥洛特罗贴治疗慢性咳嗽患儿效果及对血清IgE水平影响 　　[摘要]目的 探究孟?司特钠联合妥洛特罗贴治疗慢性咳嗽患儿的效果及对血清IgE水平的影响。方法 选取2015年1月～2017年3月我院收治的70例慢性咳嗽患儿作为研究对象，采用随机数字表法将其分为实验组和对照组，每组各35例。对照组患儿给予妥洛特罗贴治疗，实验组患儿在对照组基础上联合应用孟鲁司特钠治疗，两组均接受4周的治疗。比较两组患儿的血清IgE水平变化情况以及疗效差异。结果 实验组患儿的治疗总有效率为91.43%，明显高于对照组的71.43%，差异有统计学意义（P0.05）。治疗后，两组患儿的血清IgE水平均明显低于治疗前，且实验组患儿的血清IgE水平明显低于对照组，差异有统计学意义（P0.05）。实验组患儿的咳嗽缓解时间与消失时间均明显短于对照组，差异有统计学意义（P0.05）。结论 在应用妥洛特罗贴进行治疗的基础上，联合使用孟鲁司特钠治疗儿童慢性咳嗽，能明显改善患儿的血清IgE水平，具有更加显著的疗效，同时有助于缩短咳嗽的缓解时间和消失时间，适合在临床上推广使用。 　　[关键词]孟鲁司特钠；妥洛特罗贴；儿童；慢性咳嗽；血清IgE 　　[中图分类号] R441.5 [文献标识码] A [文章编号] 1674-4721（2018）4（b）-0139-03 　　Effect of Montelukast Sodium combined with Tolobuterol Patch in the treatment of children with chronic cough and its effect on serum IgE level 　　WANG Shao-yi GUO Wei-zhong HUANG Chan-juan 　　Department of Paediatrics，the Fourth People′s Hospital of Nanhai District in Foshan City，Guangdong Province，Foshan 528211，China 　　[Abstract]Objectives To investigate the effect of Montelukast Sodium combined with Tolobuterol Patch in the treatment of children with chronic cough and the effect on serum IgE level.Methods A total of 70 children with chronic cough treated in our hospital from January 2015 to March 2017 were selected as subjects.They were randomly divided into experimental group and control group by random number table method，with 35 cases in each group.The control group was treated with Tolobuterol Patch.The children in the experimental group were treated with Montelukast Sodium on the basis of the control group，and the two groups were treated for 4 weeks.The changes of serum IgE level and the curative effect were compared between the two groups.Results The total effective rate of the experimental group was 91.43%，which was significantly higher than that of the control group （71.43%），the difference between the two groups was statistically significant （P0.05）.After treatment，the serum IgE level of both groups were significantly lower than those before treatment，and the serum IgE level of the chi