宫腔镜辅助诊刮对子宫内膜癌患者癌细胞播散及预后临床分析.docVIP

宫腔镜辅助诊刮对子宫内膜癌患者癌细胞播散及预后临床分析 　　[摘要] 目的 研究宫腔镜辅助诊刮对子宫内膜癌患者癌细胞播散和预后状况的影响。 方法 选取2007年1月～2009年6月在我院进行治疗的110例子宫内膜癌患者，随机分为实验组和对照组，实验组患者行宫腔镜辅助分段诊刮，对照组患者行单纯分段诊刮，明确诊断后均进行手术治疗，并留取腹腔冲洗液查找癌细胞。比较两组患者癌细胞在腹腔内的播散状况和3年、5年内复发和死亡状况进行效果评价。 结果 实验组和对照组患者腹腔内癌细胞阳性发生率分别为9.09%（5/55）和7.27%（4/55），差异无统计学意义；实验组和对照组患者3年复发率分别7.27%（4/55）和5.45%（3/55），死亡率分别为3.64%（2/55）和1.82%（1/55），5年复发率分别为10.91%（6/55）和9.09%（5/55），死亡率分别为7.27%（4/55）和5.45%（3/55），差异无统计学意义。 结论 宫腔镜辅助分段诊刮术不会增加癌细胞播散风险，对患者预后不会产生负面影响，治疗安全可靠，建议在临床上推广应用。 　　[关键词] 宫腔镜辅助诊刮；癌细胞播散；预后 　　Clinical analysis of prognosis and metastasis of cancer cells in patients with endometrial carcinoma diagnosed by hysteroscopy 　　WANG Haiying1 WU Xiaojie2 　　1.Department of Gynaecology and Obstetrics，Jiaxing City Xiuzhou District Maternal and Child Health Hospital，Jiaxing 314031，China；2.Department of Gynaecology and Obstetrics，Jiaxing City Maternal and Child Health Hospital， Jiaxing 314000，China 　　[Abstract] Objective To study effect on the prognosis and metastasis of cancer cells in patients with endometrial carcinoma diagnosed by hysteroscopy. Methods All 110 patients with endometrial carcinoma who treatment in our hospital from January 2007 to June 2009 were selected and randomly divided into experimental group and control group. Patients of the experimental group were fractional curettaged assisted by hysteroscopy， patients of control group were fractional curettaged without the use of hysteroscopy， after definite diagnosis， surgical treatment were performed， and peritoneal fluid were remained to find cancer cells. Condition of cancer spread into abdomen and recidivation and death over 3 and 5 years of the two groups were compared. Results The positive rate of cancer cells in abdominal cavity of the two groups were 9.09%（5/55） and 7.27%（4/55）， the difference of the two groups showed no significance. Three-year recurrence rate and mortality of experimental group and control group were 7.27%（4/55），5.45%（3/55），3.64%（2/55）and 1.82%（1/55），and five-year recurrence r