注射用丹参多酚酸盐联合巴曲酶治疗进展性脑卒中疗效观察.docVIP

注射用丹参多酚酸盐联合巴曲酶治疗进展性脑卒中疗效观察 　　【摘要】 目的 研究注射用丹参多酚酸盐联合巴曲酶治疗进展性脑卒中的临床效果。方法 40例进展性脑卒中患者， 随机分为对照组与观察组， 各20例。对照组给予常规吸氧、调脂、脱水、清除自由基以及营养脑神经等治疗， 观察组同时采用注射用丹参多酚酸盐与巴曲酶联合治疗。比较两组的治疗效果。结果 观察组治疗总有效率（80.0%）高于对照组（50.0%）（P0.05）；治疗后观察组美国国立卫生院神经功能缺损评分（NIHSS）及日常生活能力（ADL）评分优于对照组（P0.05）。结论 在进展性脑卒中治疗用药方案中， 注射用丹参多酚酸盐联合巴曲酶疗效确切， 可有效改善患者神经功能缺损症状， 改善其生活质量， 值得临床加以推广应用。 　　【关键词】 进展性脑卒中；注射用丹参多酚酸盐；巴曲酶 　　DOI：10.14163/j.cnki.11-5547/r.2016.17.002 　　Observation of curative effect by salvianolate for injection combined with batroxobin in the treatment of progressive stroke GAN Li. Department of General Medicine， Shanwei City Second People’s Hospital， Shanwei 516600， China 　　【Abstract】 Objective To research clinical effect by salvianolate for injection combined with batroxobin in the treatment of progressive stroke. Methods A total of 40 progressive stroke patients were randomly divided into control group and observation group， with 20 cases in each group. The control group received conventional therapy by oxygen inhalation， lipid regulation， dehydration， free radical scavenging and cranial nerve nourishing， and the observation group received additional salvianolate for injection combined with batroxobin. Curative effects of the two groups were compared. Results The observation group had higher total effective rate （80.0%） than the control group （50.0%） （P0.05）. After treatment the observation group had higher national institutes of health stroke scale （NIHSS） and activities of daily living （ADL） scores than the control group （P0.05）. Conclusion Combination of salvianolate for injection and batroxobin in treating progressive stroke provides precisely curative effect. This method can improve neurologic impairment and quality of life in patients， and it is worth clinical promotion and application. 　　【Key words】 Progressive stroke； Salvianolate for injection； Batroxobin 　　进展性脑卒中是指发病后24～72 h内患者神经功能缺损症状呈进行性加重的一种难治性脑血管疾病， 脑卒中患者中进展性脑卒中发病率约占20%[1]。本病具有较高的致残、致死率， 对患者生命健康与生存质量造成严重影响和威胁。本文主要观察研究注射用丹参多酚酸盐联合巴曲酶