水溶性维生素联合小儿复方氨基酸治疗手足口病疗效观察.docVIP

水溶性维生素联合小儿复方氨基酸治疗手足口病疗效观察 　　[摘要]目的探讨水溶性维生素联合小儿复方氨基酸治疗手足口病的临床疗效。方法采用随机对照试验，选择手足口病的患儿80例，随机分为对照组40例和治疗组40例，观察其临床疗效。结果水溶性维生素联合小儿复方氨基酸治疗患儿，治疗组体温恢复正常、手足皮疹、口腔疱疹消退的时间及住院天数均较对照组缩短，差异有统计学意义(P0.05)；而并发症的发生率也较对照组低（P＜0.01）。结论水溶性维生素联合小儿复方氨基酸治疗手足口病疗效确切，且未发现不良反应。 　　[关键词]水溶性维生素； 小儿复方氨基酸； 手足口病； 疗效观察 　　[中图分类号] R512.5[文献标识码]A [文章编号] 1005-0515（2010）-11-233-02 　　 　　oint compound amino acid water-soluble vitamin therapy in children Efficacy of hand, foot and mouth disease 　　 　　LI Fu -lan, CHEN Li-qing, LI Zhi-jun, LI Yan 　　(Chengdu No.5 Peoples Hospital,Sichuan Chengdu611130,China) 　　[Abstract]ObjectiveTo investigate the combined water-soluble vitamin compound amino acid treatment in children the clinical efficacy of hand, foot and mouth disease. MethodsA randomized controlled trial, selected children with hand, foot and mouth disease in 80 patients, 40 patients were randomly divided into control group and treatment group of 40 patients, clinical efficacy. Results The water-soluble vitamin compound amino acid treatment of pediatric patients combined treatment group, body temperature returned to normal, hand, foot and skin rashes, oral herpes regression of the time and hospital stay shorter than in the control group, the difference was statistically significant (p 0.05); and complications There was also a lower than the control group (P 0.01).ConclusionThe combined water-soluble compound of amino acids in children is effective treatment of hand, foot and mouth disease, and no adverse reactions found. 　　[Keywords] Water-soluble vitamins; Pediatric compound amino acids; Hand, foot and mouth disease; Efficacy 　　 　　手足口病是由肠道病毒、通常为柯萨奇A 16型(CoxA16)、少数为A5、A10等引起的一种以手足口部位出现水疱为特征的传染病[1]。多发于学龄前儿童，尤以3岁以下年龄组发病最高，多在夏秋季节流行。主要症状表现为手、足、口腔等部位的斑丘疹、疱疹，少数重症病例可出现无菌性脑膜炎、脑炎、脑脊髓膜炎、肺水肿、循环障碍等。少年儿童和成人感染后多不发病，但能够传播病毒。我院用水溶性维生素联合小儿复方氨基酸治疗手足口病患儿80例，疗效理想，现报道如下。 1 资料与方法 　　1.1一般资料80例患儿均为我院手足口病隔离病房2009年3月～2010年7月的手足口病(均以报卡)住院患儿，随机分为对照组和治疗组。对照组40例，其中男22例，女18例；年龄6月～6岁，平均年龄2.6岁；治疗组40例，其中男24例，女16例；年龄6月～5.5岁，平均年龄2