微创下置管抽吸液化引流手术治疗脑出血对患者神经功能炎性因子水平影响.docVIP

微创下置管抽吸液化引流手术治疗脑出血对患者神经功能炎性因子水平影响 　　【摘要】 目的 探讨脑出血治疗中应用微创下置管抽吸液化引流手术对其神经功能、炎性因子水平的临床影响。方法 84例脑出血患者， 按随机分配原则分为参考组与实验组， 各42例。参考组患者采取内科保守治疗， 实验组患者在参考组基础上给予微创下置管抽吸液化引流手术治疗。对两组患者治疗前后的神经功能缺损评分以及治疗后炎性因子水平进行比较观察。结果 治疗前， 两组患者的神经功能缺损评分比较差异无统计学意义（P0.05）；治疗后， 实验组患者的神经功能缺损评分（19.52±3.78）分明显低于参考组的（28.42±4.26）分， 差异具有统计学意义（P0.05）。治疗后， 实验组患者的血清超敏C反应蛋白（hs-CRP）、肿瘤坏死因子-α（TNF-α）、白介素-6（IL-6）分别为（23.63±10.62）、（35.87±11.36）、（18.75±8.24）ng/L， 明?@优于参考组的（40.52±11.45）、（46.78±8.71）、（34.74±8.72）ng/L， 差异具有统计学意义（P0.05）。结论 微创下置管抽吸液化引流手术对脑出血患者神经功能、炎性因子水平的改善效果理想， 值得推广。 　　【关键词】 微创下置管抽吸液化引流手术；脑出血；神经功能；炎性因子水平；影响效果 　　DOI：10.14163/j.cnki.11-5547/r.2018.09.007 　　【Abstract】 Objective To investigate the clinical effect of minimally invasive suction tube aspiration and drainage on the level of nerve function and inflammatory factors level in patients with cerebral hemorrhage. Methods A total of 84 patients with cerebral hemorrhage were randomly divided into control group and experimental group， with 42 cases in each group. The control group received medical conservative treatment， and the experimental group received minimally invasive suction tube aspiration and drainage on the basis of the control group. The nerve function defect score before and after treatment and inflammatory factors level after treatment were compared and observed in two groups. Results Before treatment， both groups had no statistically significant difference in nerve function defect score （P0.05）. After treatment， the experimental group had obviously lower nerve function defect score as （19.52±3.78） points than （28.42±4.26） points in the control group， and the difference was statistically significant （P0.05）. After treatment， the experimental group had serum hypersensitive C reactive protein （hs-CRP）， tumor necrosis factor - α （TNF-α）， and interleukin - 6 （IL-6） respectively as （23.63±10.62）， （35.87±11.36） and （18.75±8.24） ng/L， which were obviously better than （40.52±11.45）， （46.78±8.71） and （34.74±8.72） ng/L in the control group， an