拉贝洛尔治疗妊娠高血压患者临床疗效及对分娩结局影响.docVIP

拉贝洛尔治疗妊娠高血压患者临床疗效及对分娩结局影响 　　[摘要]目的 探讨拉贝洛尔治疗妊娠高血压的临床效果及对分娩结局的影响。 方法 选取我院收治的120例妊娠高血压患者随机分为观察组和对照组，对照组采用常规方法治疗，观察组在对照组基础上加用拉贝洛尔治疗，比较两组患者治疗效果及对分娩结局影响。 结果 观察组治疗后收缩压和舒张压均低于对照组，两组比较差异有统计学意义（P0.05）；观察组不良妊娠结局发生率为6.67%，明显低于对照组21.67%的发生率，两组比较差异有统计学意义（P0.05）；观察组患者分娩后新生儿1、5min Apgar评分均高于对照组，两组比较有统计学意义（P0.05）。 结论 拉贝洛尔治疗妊娠高血压可有效降低血压，减少不良妊娠结局发生率，提高胎儿出生质量，具有显著临床治疗效果，值得在临床中 推广应用。 　　[关键词]拉贝洛尔；妊娠高血压；疗效 　　[中图分类号] R714 [文献标识码] B [文章编号] 2095-0616（2015）15-112-03 　　[Abstract] Objective To explore the clinical effect of labetalol in the treatment of patients with pregnancy-induced hypertension and its influence on delivery outcome. Methods 120 patients with pregnancy-induced hypertension who were admitted to our hospital were randomly divided into observation group and control group. The control group was treated with conventional treatment， and the observation group was further treated with labetalol. The curative effect and its influence on delivery outcome of two groups were compared. Results Systolic pressure and diastolic pressure of observation group after treatment were both lower than those of control group， and the difference was statistically significant （P0.05）. Incidence rate of adverse pregnancy outcomes of observation group was 6.67%， which was significantly lower than 21.67% of control group， and the difference was statistically significant （P0.05）. The neonates Apgar scores at 1min and 5mins of observation group were both higher than those of control group， and the difference was statistically significant（P0.05）. Conclusion Labetalol in the treatment of patients with pregnancy-induced hypertension can effectively lower blood pressure and incidence rate of adverse pregnancy outcome to improve neonates quality， which has significant clinical effect and is worthy of clinical promotion and application. 　　[Key words] Labetalol； Pregnancy-induced hypertension； Curative effect 　　妊娠高血压指发生在妊娠20周后出现高血压，为妊娠期特有疾病，随着分娩结束疾病消失，临床发病率较高，严重影响患者及胎儿生命健康[1]。临床表现为血压升高、水肿、蛋白尿等，如不进行及时有效治疗，可能