温针灸治疗类风湿关节炎效果及对TNF―αIL―6IL―37影响.docVIP

温针灸治疗类风湿关节炎效果及对TNF―αIL―6IL―37影响 　　[摘要]目的 探讨温针灸治疗类风湿关节炎（RA）（痛痹）的效果及对患者血清TNF-α、IL-6、IL-37水平的影响。方法 将2013年9月至2017年1月于我院就诊的92例RA患者纳入研究并据随机数字表法分组，对照组46例采用单纯西药治疗，观察组46例联合温针灸治疗。比较临床疗效及炎症因子情况。结果 治疗后，两组患者的TNF-α、IL-37、IL-6水平降低，观察组的上述指标明显低于对照组（P0.05）；两组患者的肿胀关节个数、关节压痛个数减少，观察组的上述指标明显少于对照组（P0.05）；观察组的总有效率为93.48%，明显高于对照组的76.09%（P0.05）。结论 温针灸治疗RA的效果显著，可改善炎症反应，值得推广。 　　[关键词]温针灸；类风湿关节炎；痛痹；炎症因子 　　[中图分类号] R593.22 [文献标识码] A [文章编号] 1674-4721（2017）11（a）-0164-03 　　The effect of needle warming moxibustion treating rheumatoid arthritis （Tongbi） and its impact on TNF-α，IL-6 and IL-37 　　HOU Xin-ju1 MA Hong-mei2 XIONG Wei1 　　1.The First Department of Rehabilitation，Hongdu Hospital of Traditional Chinese Medicine in Nanchang City of Jiangxi Province，Nanchang 330008，China；2.Department of Acupuncture，Hongdu Hospital of Traditional Chinese Medicine in Nanchang City of Jiangxi Province，Nanchang 330008，China 　　[Abstract]Objective To investigate the effect of needle warming moxibustion treating rheumatoid arthritis （RA，Tongbi） and its impact on TNF-α，IL-6 and IL-37.Methods From September 2013 to January 2017，92 patients diagnosed with cold-damp obstruction type of RA were included in our hospital and were randomly divided into two groups on the basis of the random data table method.The control group （n=46） received western medicine only，while the observation group （n=46） received needle warming moxibustion treatment.Furthermore，the clinical efficacy and inflammatory factors were compared.Results After treatment，the level of TNF-α，IL-6 and IL-37 in the two groups were decreased，and those indexes in the observation group were significantly decreased than those in the control group （P0.05）.The number of joints swelling and joint tenderness were decreased in both groups，and the indexes in the observation group were significantly fewer than those in the control group （P0.05）.The total effective rate of the observation group was 93.48%，which was significantly higher than the control group （76.09%） （P0