生肌象皮膏对感染创面愈合影响.docVIP

生肌象皮膏对感染创面愈合影响 　　[摘要] 目的 探讨生肌象皮膏治疗感染创面的疗效，总结经验。 方法 将200例患者随机分为两组，治疗组103例，创面涂抹生肌象皮膏；对照组97例，外科常规换药，优锁纱布湿敷创面。两组患者分别于用药前及治疗后第4周采集创面分泌物做细菌培养，4周后评估创面愈合情况，观察比较总体疗效及细菌培养阳性率。 结果 两组治愈率分别为73.97％、42.27％（χ2=20.44，P 0.01）；两组细菌培养阳性率分别为12.62％、34.02％（χ2=12.92，P 0.01），具有显著统计学意义。 结论 生肌象皮膏能够有效促进感染创面愈合。 　　[关键词] 生肌象皮膏；感染创面；愈合 　　[中图分类号] R244.9 [文献标识码] B [文章编号] 1673-9701（2012）06-0145-02 　　 　　Effects of Shengji Xiangpi mastic upon infected wound 　　ZHOU Taiji 　　Department of Orthopaedics，Worker’s Hospital of Henan Quality and Engineering Vocational College，Pingdingshan 467000，China 　　[Abstract] Objective To evaluate the curative effect on the infected wound by using Shengji Xiangpi Mastic and summing up the experience and lessons during the process. Methods All of 200 cases were divided into treatment group (103 cases) used Shengji Xiangpi Mastic and control group (97 cases) received surgical conventional essence, yousuo gauze. After four weeks, each groups secretions would be taken again for bacterial culture compared with those had been taken at the very beginning. Meanwhile, the healing conditions would be evaluated by observing the overall effect and positive rate of bacterial culture. Results Cure rates of the two groups were 73.97％ (76 cases) and 42.27％ (41 cases), χ2=20.44, P 0.01; The positive rates of bacterial culture were 12.62％ (13 cases) and 34.02％ (33 cases), χ2=12.92, P 0.01, and there was a statistically difference. Conclusion Shengji Xiangpi Mastic can effectively promote the healing of wound infection. 　　创伤合并创面感染属常见病及多发病，一直是骨科治疗中颇为棘手的问题。我院2006年10月～2009年7月采用生肌象皮膏治疗200例创面感染患者，取得良好疗效，现总结如下。 　　1 资料与方法 　　1.1 一般资料 　　参照《实用医院感染管理手册》[1]，将200例患者随机分为两组，治疗组103例，男75例，女28例；年龄10～65岁，平均33岁。发病部位手19例，上臂10例，前臂15例，躯干9例，大腿20例，小腿17例，足部13例。对照组97例，男64例，女33例；年龄16～63岁者，平均35岁。发病部位手8例，上臂11例，前臂7例，躯干7例，大腿31例，小腿19例，足部14例。创面大小：治疗组平均20.3 cm2，对照组平均21.7cm2。致伤原因：交通事故伤101例，矿山伤53例，机械伤27例，医源性感染19例。以上资料经检验差异无统计学意义。 　　1.2 方法 　　1.2.1 治疗组 换药前生理盐水清洁创面，适当剪除失活组织，根据溃疡面大小，涂一薄层生肌象皮膏[天津医院制剂，津药制字（2001）Z第0