祛瘀化痰方对多囊卵巢综合征患者糖脂代谢及激素水平影响.docVIP

祛瘀化痰方对多囊卵巢综合征患者糖脂代谢及激素水平影响 　　[摘要]为了研究祛瘀化痰方对多囊卵巢综合征患者糖脂代谢及激素水平的影响。选择2013年3月至2014年7月在浙江青田县中医医院接受治疗的痰湿型多囊卵巢综合征患者93例，根据随机数字表分为对照组和观察组，观察组患者口服祛瘀化痰方治疗，对照组采用二甲双胍治疗。结果表明观察组患者总有效率显著高于对照组（χ2=632，P0.05）。治疗后观察组患者中医证候评分显著低于对照组（t=13.865，P0.05）。治疗后观察组患者BMI，TG，TC均显著低于对照组（P0.05），治疗后2组患者HDL水平差异不显著。治疗后观察组患者FSH，LH和T水平均显著低于对照组（P0.05）。组内比较，治疗后2组患者FBG和INS均显著降低（P0.05）；治疗后观察组患者FBG较对照组显著偏低（t=3.981，P0.05），观察组INS水平显著高于对照组（t=6.472，P0.05）。该研究可得出结论，祛瘀化痰方治疗多囊卵巢综合征具有较好的临床疗效，不仅能够改善多种性激素分泌情况，还能调节机体糖脂代谢，从多个方面发挥治疗作用，值得临床推广应用。 　　[关键词]祛瘀化痰方；多囊卵巢综合征；糖脂代谢；性激素 　　[Abstract]To study the effect of prescription for removing blood stasis and resolving phlegm on lipid metabolism and hormone levels of patients with polycystic ovary syndrome. Totally 93 cases of patients with polycystic ovary syndrome treated in our hospital from March 2013 to July 2014 were randomly divided into control group and observation group. The observation group was treated by oral administration of Quyu Huatan decoction， while the control group was treated with metformin. The result indicated that the total effective rate of the observation group was significantly higher than that of the control group（χ2=632， P0.05）. After treatment， the score of syndrome for traditional Chinese medicine in the observation group was significantly lower than the control group（t=13.865，P0.05）. After treatment， the levels of TG， BMI， TC in the observation group were significantly lower than the control group（P0.05）， and the difference of HDL between the two groups were not significantly. After treatment， the levels of FSH， LH and T in the observation group were significantly lower than those in the control group（P0.05）. After treatment， FBG and INS in the two groups were significantly decreased（P0.05）； the FBG in the observation group was significantly lower than that in the control group（t=3.981， P0.05）， and the INS level in the observation group was significantly higher than that in the control group（t=6.472， P0.05）. In this study， we can find that the