突发性耳聋早期治疗中激素应用及疗效评估报道.docVIP

突发性耳聋早期治疗中激素应用及疗效评估报道 　　[摘要] 目的 探讨激素在突发性耳聋早期治疗中的作用。方法 方便选取2011年11月―2014年4月期间66例于该院进行治疗的突发性耳聋患者作为该的研究对象，随机分成观察组和对照组，观察组24例，对照组42例。两组患者均予以地塞米松静脉滴注，其中对照组加以利多卡因、丹参或灯盏花素、ATP静脉滴注，而观察组用或不用利多卡因、丹参或灯盏花素、ATP等治疗。对比两组患者的气导纯音听阀值和治疗有效率。 结果 治疗后，观察组患者的PTA改善程度与对照组，差异无统计学意义，P0.05。结论 采用激素治疗突发性耳聋疗效显著，值得临床推广应用。 　　[关键词] 激素；突发性耳聋；效果 　　[中图分类号] R764.437 [文献标识码] A [文章编号] 1674-0742（2016）03（c）-0086-02 　　Curative Effect Evaluation of Hormone in the Early Treatment of Sudden Deafness 　　LU Xin-min 　　Department of Otorhinolaryngology， Yangzhou Peoples Hospital， Yangzhong， Jiangsu Province， 212200 China 　　[Abstract] Objective To discuss the effect of hormone in the early treatment of sudden deafness. Methods 66 cases of patients with sudden deafness treated in our hospital from November 2011 to April 2014 were selected as the research object and randomly divided into the observation group with 24 cases and the control group with 42 cases， both groups were given the intravenous drip of dexamethasone， and the control group were given the intravenous drips of lidocaine， salvia miltiorrhiza， breviscapine and ATP on this basis， while the observation group were treated with lidocaine， salvia miltiorrhiza， breviscapine and ATP or not， the airflow pure tone hearing thresholds and treatment effective rates of the two groups were compared. Results After treatment， the difference in the improvement degree of PTA between the observation group and the control group was not obvious without statistical significance， P 0.05. Conclusion The curative effect of hormone in treatment of sudden deafness is obvious， which is worth clinical promotion and application. 　　[Key words] Hormone； Sudden deafness； Effect 　　突发性耳聋是以72 h内突然发生的听力下降为特征的一种感音神经性聋，其病因不明，程度不一，为耳鼻喉科常见的疾病，严重影响患者的正常生活，应及时采取有效的治疗措施。该研究主要探讨激素在突发性耳聋早期治疗中的作用，现报道如下。 　　1 资料与方法 　　1.1 一般资料 　　方便选取2011年11月―2014年4月期间66例于该院进行治疗的突发性耳聋患者作为该次的研究对象，随机分成观察组和对照组，观察组24例，对照组42例。其中观察组24例患者男女比例为14：8；年龄为19～78岁，平均年龄（46.4±2.3）岁；平均治疗时间（10±1.7）d。对照组42例患者男女比例为28：14；年龄为18～8