红藤汤对盆腔炎性疾病相关炎性因子及临床疗效研究.docVIP

红藤汤对盆腔炎性疾病相关炎性因子及临床疗效研究 　　DOI：10.16662/j.cnki.1674-0742.2017.09.172 　　[摘要] 目的 研究红藤汤治疗慢性盆腔炎后血液流变学及相关炎性因子变化，以阐述临床疗效。 方法 回顾性分析该院妇科2015年12月―2016年11月收治的慢性盆腔炎患者168例病历资料，观察组87例常规治疗的基础上辅以红藤汤治疗，对照组81例给予常规治疗。观察两组患者血液流变学和血浆炎症因子IL-6和TNF-α水平的变化，并对治疗效果进行评价。结果 经治疗4周后，观察组不同切变速率下的全血黏度为（9.22±0.16）、（5.67±0.36）、（4.17±0.54）mPa?s，IL-6和TNF-α水平分别为（19.48±4.71）pg/mL和（89.51±17.95）pg/mL，均显著低于对照组，差异有统计学意义（P0.05）。经治疗观察组总有效率为94.25%，对照组总有效率为75.31%。观察组总有效率显著高于对照组，差异有统计学意义（χ2=3.354，P0.05）。结论 红藤汤治疗慢性盆腔炎疗效显著。 　　[关键词] 红藤汤；慢性盆腔炎；炎性因子；血液流变学 　　[中图分类号] R4 [文献标识码] A [文章编号] 1674-0742（2017）03（c）-0172-03 　　Research on Sargentglory Decoction on the Pelvic Inflammatory Disease Related Inflammatory Factors and Clinical Curative Effect 　　LI Qing-xian 　　Department of Gynecology and Obstetrics， Putuo District Central Hospital， Shanghai， 200062 China 　　[Abstract] Objective To research the hemorheology and related inflammatory factors changes after the sargentglory decoction in treatment of chronic pelvic inflammatory disease. Methods 168 cases of patients with chronic pelvic inflammatory disease admitted and treated in our hospital from December 2015 to November 2016 were retrospectively analyzed and divided into two groups， the control group with 87 cases were treated with sargentglory decoction on the basis of the routine treatment， while the control group with 81 cases adopted the routine treatment， and the changes of hemorheology and plasma inflammatory factors IL-6 and TNF-αlevels of the two groups were observed and the treatment effect was evaluated. Results After four-week treatment， the whole blood viscosity at different shear rates， IL-6 and TNF-α levels were respectively （9.22±0.16），（5.67±0.36），（4.17±0.54）mPa?s，（19.48±4.71）pg/mL and（89.51±17.95）pg/mL， which were obviously lower than that in the control group， and the differences between groups were statistically significant（P0.05）， after treatment， the total effective rate in the observation group was obviously higher than that in the control group