立体定向穿刺引流术治疗少量基底节高血压脑出血临床研究.docVIP

立体定向穿刺引流术治疗少量基底节高血压脑出血临床研究 　　【摘要】 目的：探讨CT引导下立体定向穿刺引流术治疗少量基底节高血压脑出血的疗效。方法：选取2010年10月-2013年12月在海洋石油总医院收治的70例基底节高血压脑出血患者，出血量20～30 mL，按照随机数字表法将其分为手术组治疗组和保守治疗组各35例，手术治疗组在CT引导下行立体定向穿刺引流术，术后应用尿激酶溶解清除血肿；保守治疗组仅给予内科药物治疗。观察比较两组患者的并发症发生情况、住院时间、治疗后NIHSS评分。结果：两组均无死亡病例，且并发症发生率比较差异无明显差异（11.4% vs 22.9%，P0.05）。手术治疗组的住院时间（19.6±4.2）d明显短于保守治疗组的（23.3±5.3）d，两组治疗后2周、1个月、3个月的NIHSS评分均明显低于治疗前，且手术治疗组治疗后2周、1个月的NIHSS评分均明显低于保守治疗组，差异均有统计学意义（P0.05）。结论：立体定向穿刺引流术治疗少量基底节高血压脑出血，创伤小，可以缩短患者住院时间，促进神经功能早期恢复，值得临床推广。 　　【关键词】 立体定向； 基底节； 高血压； 脑出血； 尿激酶 　　Clinical Research of Stereotactic Puncture and Drainage in the Treatment of Little Hypertensive Cerebral Hemorrhage of Basal Ganglia/GAO Wei，YANG Xue-jun，SUN Ming-li.//Medical Innovation of China，2014，11（28）：001-004 　　【Abstract】 Objective：To investigate the therapeutic effect of CT-guided stereotactic puncture and drainage in treatment of little hypertensive cerebral hemorrhage of basal ganglia.Method：70 patients with little hypertensive cerebral hemorrhage of basal ganglia in Ocean Petroleum General hospital from October 2010 to December 2013 were selected，the amount of bleeding was 20-30 mL，they were divided into the operation treatment group and conservative treatment group according to the random number table method，35 cases in each group.The operation treatment group was given CT-guided stereotactic puncture and drainage treatment，followed by thrombolysis using urokinase.The conservative treatment group was given internal medicine treatment alone.The incidence of complications，hospitalization days，NIHSS score of the two groups after the treatment were observed and compared.Result：There was no cases died，and no difference in the incidence of complications （11.4% vs 22.9%，P0.05）in the two groups.The average hospitalization days in operation treatment group was （19.6±4.2）d，it was significantly shorter than （23.3±5.3）d in conservative treatment group，the NIHSS score 2 weeks，1 month，3 months after treatment of two groups were significantly lower than those