茵陈蒿汤加减辅治新生儿病理性黄疸临床研究.docVIP

茵陈蒿汤加减辅治新生儿病理性黄疸临床研究 　　[摘要] 目的 探讨茵陈蒿汤加减辅治新生儿病理性黄疸的疗效与安全性。 方法 选取病理性黄疸患儿192例，随机分为观察组与对照组各96例。对照组给予西医常规疗法，观察组在此基础上辅以茵陈蒿汤加减治疗。比较两组治疗前后血胆红素水平和消退情况、不良反应。结果 观察组治疗后日均胆红素降低值大于对照组，胆红素恢复至正常水平时间小于对照组（P＜0.05）。观察组与对照组总有效率分别为94.79％、88.54％（P＜0.05）。 结论 茵陈蒿汤加减辅治新生儿病理性黄疸具有较好的疗效，可降低患儿血清胆红素水平，消退黄疸症状，具有较高的安全性。 　　[关键词] 新生儿；病理性黄疸；茵陈蒿汤 　　[中图分类号] R722.17[文献标识码] B[文章编号] 1673-9701（2014）15-0085-03 　　 　　Clinical study on adjuvant treatment of neonatal pathological jaundice by Yinchenhao decoction 　　SANG Yaqing1 TIAN Weiqiang1 FENG Jian2 　　1.Pharmacy Department of Lishui Central Hospital in Zhejiang Province, Lishui 323000 ,China;2. Pharmacy College of Zhejiang Chinese Medicine University, Hangzhou 310053, China 　　[Abstract] Objective To explorer the curative effect and safety on adjuvant treatment of neonatal pathological jaundice by Yinchenhao Decoction. Methods A total of 192 cases with neonatal pathological jaundice were selected, and were randomly divided into observation group and control group, with 96 cases in per group. Control group were given conventional treatment of Western medicine, and observation group were given adjuvant treatment by Yinchenhao Decoction based on control group. Two groups’ serum bilirubin level and extinction were compared before and during treatment, also adverse reactions were recorded. Results After treatment, bilirubin decrease values everyday in observation group were higher than that of control group, time of serum bilirubin returning to normal level was less than that of control group(P＜0.05). Total effective rate in observation groupand control group was 94.79% and 88.54% respectively(P＜0.05). Conclusion It has good clinical curative on adjuvant treatment of neonatal pathological jaundice by Yinchenhao Decoction, for it decreases patients’ serum bilirubin rapidly, and eliminates jaundice symptom, also has higher safety. 　　[Key words] Newborn; Pathological jaundice; Yinchenhao decoction黄疸是新生儿期临床常见症状，约50%~80%的新生儿可出现黄疸，其原因在于胆红素代谢障碍引发血胆红素水平增高而导致皮肤、巩