耳鸣频率对慢性主观性耳鸣患者药物治疗效果相关性研究.docVIP

耳鸣频率对慢性主观性耳鸣患者药物治疗效果相关性研究 　　[摘要] 目的 探讨不同耳鸣频率对慢性主观性耳鸣患者药物治疗效果的影响。 方法 选取2013年9月～2016年9月期间在耳鼻喉科门诊和住院治疗的慢性主观性耳鸣患者62例，根据耳鸣频率分成高、中、低三组，其中高频率组21例，中频率组22例，低频率组19例。三组患者均给予银杏叶提取物+地塞米松治疗。治疗3周后比较各组患者治疗前后耳鸣响度的改善情况，并对耳鸣频率与耳鸣预后的相关性?M行分析。 结果 三组患者经药物治疗后耳鸣响度改善率均较治疗前有显著改善，其中高频率组耳鸣响度改善率为（0.25±0.05），中频率组（0.47±0.06），低频率组为（0.68±0.07），低频率组耳鸣响度改善率高于中频率组和高频率组，中频率组高于高频率组（P均0.05）；高频率组有效率为57.1%，中频率组有效率为81.8%，低频率组有效率为94.7%，低频率组和中频率组经药物治疗后有效率均明显优于高频率组（P0.05）。 结论 不同耳鸣频率的慢性主观性耳鸣患者的药物治疗效果存在一定差异，银杏叶提取物联合地塞米松治疗慢性主观性耳鸣有效，其中对低中频率耳鸣的疗效较高频率耳鸣更佳。 　　[关键词] 耳鸣频率；慢性主观性耳鸣；药物治疗；相关性 　　[中图分类号] R764 [文献标识码] A [文章编号] 2095-0616（2017）15-70-04 　　[Abstract] Objective To explore the effect of different tinnitus frequencies on drug therapy in patients with chronic subjective tinnitus. Methods 62 patients of chronic subjective tinnitus in the Department of ENT， outpatient and inpatient treatment from September 2013 to September 2016 were selected and divided into high frequency group（21 cases），middle frequency group（22 cases）and low frequency group（19 cases） according to the frequency of tinnitus.All the patients in the three groups of patients were treated with Ginkgo biloba extract plus dexamethasone.After 3 weeks of treatment，the improvement of tinnitus volume was observed before and after treatment in each group.The correlation between tinnitus frequency and prognosis of tinnitus were analyzed. Results The improvement rate of tinnitus loudness in the three groups after treatment was better than that before treatment.Among them，the improvement rate of tinnitus loudness in the high frequency group was （0.25±0.05）， the middle frequency group was （0.47±0.06），and the low frequency group was （0.68±0.07）.The improvement rate of loudness in the low frequency group was higher than that in the intermediate frequency group and the high frequency group，and the middle frequency group was higher than that of the high frequency group（P 　　[Key words] Tinnitus frequency；Chronic subjective tinnitus；Drug therapy；Correlation 　　耳鸣是一