肺动脉高压患者院外服用靶向治疗药物依从性研究.docVIP

肺动脉高压患者院外服用靶向治疗药物依从性研究 　　【中图分类号】R543.2 【文献标识码】A 【文章编号】1672-3783（2013）11-0578-02 　　【摘要】 目的 探讨肺动脉高压患者出院后服用靶向治疗药物的依从性及其影响因素，为临床护理提供指导依据。方法 本研究入选了2010年1月～12月在我科就诊首次确诊第一大类肺动脉高压并接受靶向治疗药物的患者202例，出院3个月后进行服药依从性及其影响因素的问卷调查，所有数据应用SPSS13.0软件包进行数据处理。结果 患者的服药依从性与患者年龄有关（P=0.04）、与受教育程度和家庭年收入有关（P0.01），与患者是否参加临床试验有关（P=0.05），影响患者服药依从性相关因素包括经济因素、对疾病认知因素、年龄因素、药物副作用等因素。结论 护理人员在进行健康教育的时候，应重视个体化差异，加强与患者和患者家属的沟通，提供多元化指导方式，提高患者的院外服药依从性。 　　【关键词】 肺动脉高压；靶向药物治疗；服药依从性 　　Study on the mediciation adherence of pulmonary arterial hypertension patients after taking targeted drug therapu outside hospital 　　【Author’s Address】Shanghai Pulmonary Hospital，Shanghai， 200433， China 　　【Abstract】 Objective Analyze the compliance and the medication adherence of pulmonary arterial hypertension patients after taking targeted drug therapy， and to provide guidance for clinical nursing. Methods The study selected 202 patients who were diagnosed the first category of pulmonary arterial hypertension and had accepted targeted therapy drugs from January to December in 2010 in our department， and doing the questionnaire about the medication compliance and influence factors after 3 months ， all data using SPSS13.0 software package for data processing. Results Compliance with the age of the patients involved （P=0.04 ）， and the level of education and family income related （P 0.01 ）， and whether patients participating in a clinical trial （P=0.05）， the effects of the medication compliance of patients with related factors including economic factors， cognitive factors of disease， age factors， drug side effects and other factors. Conclusion Attention should be paid to individual differences in health education， and strengthen communication with patients and families to provide diversified ways of guidance， improving drug compliance of patients. 　　【Key words】 Pulmonary arterial hypertension； Targeted drug therapy； Medication adherence 　　肺动脉高压（pulmonary arterial hypertension，PAH）是肺动脉压力进行性升高为特点的一类严重威胁患者生命安全的恶性肺血管疾病，是肺高血压病临