美多芭方案在治疗帕金森病上疗效分析.docVIP

美多芭方案在治疗帕金森病上疗效分析 　　[摘要] 目的 分析探讨美多芭方案在治疗帕金森病上的临床疗效治疗效果。方法 方便选取2012年5月―2014年5月间该院收治的100例帕金森患者为例，随机分为对照组和观察组。对照组以服用美多芭进行治疗，观察组则在对照组的基础上配合服用吡贝地尔，对比分析两组疗效。 结果 观察组患者的总有效率为88%，对照组的有效率为72%。观察组的治疗效果同对照组相比更好，差异有统计学意义。两组患者在治疗过程中都没有不良反应发生。治疗5个月后，调查评分下降程度方面观察组明显低于对照组，差异具有统计学意义。结论 相比单纯的服用美多芭进行治疗，服用美多芭配合多巴胺能激动剂的方案更能帮助帕金森患者治疗疾病，该方案可以有效的提高治疗效率，适合在临床上采取广泛应用。 　　[关键词] 美多芭；帕金森；治疗方案 　　[中图分类号] R74 [文献标识码] A [文章编号] 1674-0742（2016）06（b）-0125-03 　　[Abstract] Objective To analysis the treatment effect of Parkinsons disease by Madopar scheme. Methods Convenient selection between May 2014 to May 2012， 100 patients were selected from our hospital， and patients were randomly divided into control group and observation group， two groups.The control group was treated by taking Madopar treatment. On the basis of the control group， the observation group cooperate with piribedil. Comparative analysis of the efficacy of the two groups. Results The total effective rate of the observation group was 87.9%， and the effective rate of the control group was 72%. The effect of the observation group was better than that of the control group， and the difference was statistically significant. There was no adverse reaction in the treatment of the two groups. After five months of treatment， the score of the observation group was significantly lower than that in the control group， and the difference was statistically significant. Conclusion Compared with pure taking Madopar treatment， Taking Madopar combined with dopamine agonists scheme can help treatment in patients with Parkinson disease， this scheme can effectively improve the treatment efficiency， suitable for clinical application. 　　[Key words] Madopar ； Parkinson ； Therapeutic regimen 　　帕金森病，也可以称作震颤麻痹，是一种常见的神经系统变性疾病，中老年患者居多。通过病理研究发现，帕金森病的病变部位在人脑的中脑位置，该处的黑质神经元变性死亡过多，无法分泌足够的递质多巴胺来维持调节神经系统的正常功能，从而引发帕金森病。帕金森病临床表现主要表现为静止性震颤，肢体僵硬，肌张力增高，运动迟缓，姿势平衡障碍等。除此之外，患者还有可能出现精神方便的临床表现，如精神恍惚，抑郁，有认知方面的障碍等，症状多样，比较复杂。帕金森病严重影响了患者的正常生活，因此应该对帕金森病给予高度重视。该文方便选取2012年5月―2014年5月间该院收治