腹腔镜下腹股沟疝围术期105例抗菌药物应用对术后感染影响.docVIP

腹腔镜下腹股沟疝围术期105例抗菌药物应用对术后感染影响 　　摘 要 目的：探讨腹腔镜下腹股沟疝围术期抗菌药物应用及无预防性应用抗菌药物对术后感染的影响。方法：根据抗菌药物使用情况，158例患者分为用药组（n=105）与未用药组（n=53），比较两组患术后感染率的差异。结果：改进后，抗菌药物应用率、术前2 h应用率、应用疗程明显低于改进前（P0.05）；用药组平均住院时间与平均住院费用均明显高于未用药组（P0.05）。结论：腹腔镜下腹股沟疝围术期抗菌药物合理应用改进显著降低围术期抗菌药物总体应用率与应用疗程，提高术前抗菌药物术前合理应用率，且无预防性应用抗菌药物在缩短住院时间、减少住院费用的前提下不增加术后感染风险。 　　关键词 腹股沟疝 围术期 抗菌药物 感染 　　中图分类号：R978.1； R656.21 文献标识码：A 文章编号：1006-1533（2015）23-0036-03 　　The effect of 105 cases of application of antimicrobial agents on the infection in laparoscopic inguinal hernia perioperative* 　　MIN Changguo**， QIU Jian， LIU Lisong， YIN Ruizhong， SHENG Shouyin， LIU Binhua， HU Wenfeng（Department of General Surgery， The Third People’s Hospital of JiuJiang City， Jiujiang 332000， China） 　　ABSTRACT Objective： To investigate the effect of perioperative application of or without prophylactic use of antimicrobial agents on the infection in laparoscopic inguinal hernia perioperative. Methods： According to the application situation of antimicrobial agents， 158 cases of patients were divided a medication group （n=105） and a non-meidication one（n=53） and the postoperative infection rate was compared between two groups. Results： The application rate and the course of antibacterial agents and preoperative 2 h application rate were significantly lower after the improvement of medication than before （P0.05）. The average length and expenses of hospitalization of the medication group were significantly higher than those of the non-meidication group （P0.05）. Conclusion： The improved reasonable use of antimicrobial agents in laparoscopic inguinal hernia perioperative can significantly reduce the overall application rate and course of antibacterial agents and improve their preoperative reasonable application rate. Furthermore， postoperative infection risk would not be increased when prophylactic use of antimicrobial agents is not applied under the premise of shortening the length of hospital stay and reducing the cost of hospitalization. 　　KEY WORDS