腹腔镜指导下小切口阑尾切除术治疗急性阑尾炎患者临床效果及对体液免疫影响.docVIP

腹腔镜指导下小切口阑尾切除术治疗急性阑尾炎患者临床效果及对体液免疫影响 　　[摘要] 目的 分析腹腔镜指导下的小切口阑尾切除术治疗急性阑尾炎患者的临床效果及对体液免疫的影响。 方法 选取急性阑尾炎患者100例，实施腹腔镜指导下的小切口阑尾切除术患者50例为观察组，实施传统开腹切除术患者50例为对照组。观察两种手术的临床效果、对体液免疫的影响。 结果 观察组患者总住院时间、首次下床时间、首次进食时间、首次排气时间、手术总时间、总出血量、切口长度均明显小于对照组（P0.05）。两组患者术后C反应蛋白（CRP）水平均明显升高（P0.05），且对照组明显高于观察组（P0.05）。两组患者术后血清前清蛋白（PA）、人免疫球蛋白M（IgM）、人免疫球蛋白G（IgG）水平均明显降低（P0.05），且观察组明显高于对照组（P0.05）。 结论 腹腔镜指导下的小切口阑尾切除术临床效果较优、体液免疫功能较好、术后并发症较少。 　　[关键词] 急性阑尾炎；腹腔镜；小切口阑尾切除术；体液免疫 　　[中图分类号] R656.8 [文献标识码] B [文章编号] 1673-9701（2018）05-0048-03 　　[Abstract] Objective To analyze the clinical effect of laparoscopic small incision appendectomy on patients with acute appendicitis and its influence on humoral immunity. Methods A total of 100 cases with acute appendicitis were selected. 50 cases who underwent laparoscopic small incision appendectomy were chosen as observation group. 50 cases undergoing traditional open excision were selected as control group. The clinical effects of the two kinds of surgery and their impact on humoral immunity were observed. Results The total length of hospital stay， first time to get out of bed， the first exhaust time， total operation time， total bleeding and incision length in the observation group were significantly less than those in the control group（P0.05）. The levels of postoperative C-reactive protein（CRP） in both groups were significantly increased（P0.05）， and the levels in the control group were significantly higher than those in the observation group（P0.05）. The levels of serum prealbumin（PA）， human immunoglobulin M（IgM） and human immunoglobulin G（IgG） were significantly decreased in both groups（P0.05）， and the level of the observation group was significantly higher than that of the control group（P0.05）. Conclusion Laparoscopic small incision appendectomy has better clinical effect， better humoral immunity and less postoperative complications. 　　[Key words] Acute appendicitis；Laparoscopy；Small incision appendectomy；Humoral immunity 　　急性阑尾炎为最常见的外科急腹症，解剖位置变化较多，若患者不能得到及时的救