神经内科帕金森病治疗最新版.ppt

（二）症状性治疗(symptomatic therapy)  I 早期PD治疗（Hoehn-Yahr I-II级） 1．何时开始用药 疾病早期若病情未对患者造成心理或生理影响，应鼓励患者坚持工作，参与社会活动和医学体疗，可暂缓用药。若疾病影响患者的日常生活和工作能力，则应开始症状性治疗。 Management of PD 2012 Olanow CW, et al. Online at: www.N 谢 谢 PD治疗的五大类药物 * DATATOP研究中，早期应用金思平治疗可延缓疾病进展（约9个月），推迟左旋多巴使用时间 *LEAP ABPI DECK This graph demonstrates the dramatic impact levodopa has had on the treatment of Parkinson’s disease (PD) since its introduction in the 1960s Compared with the pre-levodopa era (untreated patients), levodopa treatment has significantly reduced the amount of severe disability and mortality associated with PD