艾滋病定点治疗机构选择生育HIV感染孕产妇临床特点分析.docVIP

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艾滋病定点治疗机构选择生育HIV感染孕产妇临床特点分析.doc

艾滋病定点治疗机构选择生育HIV感染孕产妇临床特点分析

艾滋病定点治疗机构选择生育HIV感染孕产妇临床特点分析   【摘要】 目的 了解?x择生育的艾滋病病毒(HIV)感染孕产妇的临床特点, 探讨预防艾滋病母婴传播的工作模式。方法 采用个案调查方法统计252例HIV感染孕产妇的相关资料, 包括社会人口学特征、HIV感染确证时间、HIV感染途径、首次CD4+ T淋巴细胞(简称CD4细胞)水平、进行母婴阻断抗反转录病毒治疗(ART)的时机, 所生婴儿随访至12~18月龄进行HIV抗体检测, 判断婴儿HIV感染情况。结果 HIV感染孕产妇以壮族为主占66.27%、初中及以下文化程度者占75.79%、无职业和灵活就业占78.57%、HIV感染确证时间以孕期为主占62.70%、经性途径感染比例高达100.00%, 首次CD4细胞200个/μl的艾滋病孕产妇占24.21% , 孕前与孕期抗病毒治疗率占87.70 %, 产时抗病毒治疗率占12.30%, 选择剖宫产分娩占53.97%, 252例婴儿均为活产, 100.00%给予人工喂养。截至2016年12月年满18月龄以上儿童有166例, 其中HIV抗体检测结果阴性有162例、检测结果阳性确证HIV感染有2例、失访有1例、死亡有1例, 校正后HIV母婴传播率为1.48%, 其余86例18月龄以下儿童正在随访检测当中。结论 早期发现HIV感染的妇女是HIV母婴阻断的关键, 初中及以下文化程度者、无职业和灵活就业人员是预防HIV母婴传播的重点人群, 适时规范的ART治疗, 结合安全分娩和人工喂养, 可以实现消除母婴传播HIV的目标。   【关键词】 艾滋病病毒;临床特点;抗反转录病毒治疗;母婴阻断   DOI:10.14163/j.cnki.11-5547/r.2017.05.097   Analysis of clinical characteristics on HIV-infected pregnant women in AIDS-designated treatment institution PANG Jun, LIU Dong-mei, WEI Shu-zhen, et al. Department of Gynaecology and Obstetrics, Guangxi AIDS Clinical Treatment Center (Nanning City Fourth People’s Hospital), Nanning 530023, China   【Abstract】 Objective To know the clinical characteristics on human immunodeficiency virus (HIV)-infected pregnant women, and to explore work patterns to prevente mother-to-child transmission of HIV. Methods Related date of 252 HIV-infected pregnant women were collected by case study method, including social demographic characteristics and HIV infection confirmed time, HIV infection route, CD4+ T cells (short for CD4 cells) level in the first time, maternal and timing of antiretroviral therapy (ART) in prevention of mother-to-child transmission, and HIV antibody in babies was detected after 12~18 months of follow-up, to confirm HIV infection status in babies. Results HIV infection was mainly of the Zhuang nationality, accounting for 66.27%, with 75.79% of junior high school and below education, 78.57% of inoccupation and flexible employment. HIV infection time was mainly during pregnant, accounting for 62.70%, with 100.00% of sexual inf

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