西咪替丁联合叶酸治疗腹泻临床效果探讨.docVIP

西咪替丁联合叶酸治疗腹泻临床效果探讨 　　DOI：10.16662/j.cnki.1674-0742.2017.07.125 　　[摘要] 目的 观察与分析西咪替丁联合叶酸治疗腹泻的临床效果。方法 方便选择该院在2014年10月―2016年10月间收治的78例腹泻患者为研究主体。根据患者入院时间，将其分成A组和B组，每组39例。A组给予西咪替丁联合叶酸治疗，B组给予思密达与乳酶生片治疗。对比两组的临床疗效、症状消失与用药时间、不良反应与复发情况。结果 A组的治疗总有效率是94.87%，B组是82.05%，对比差异有统计学意义（P0.05）。A组的症状消失时间与用药时间明显短于B组，对比差异有统计学意义（P0.05）。A组的不良反应发生率是2.56%，B组是10.26%；停药后，A组的复发率是5.13%，B组是25.64%，对比差异有统计学意义（P0.05）。结论 对于腹泻患者，采用西咪替丁联合叶酸治疗具有确切疗效，且症状缓解快、治疗时间短、不良反应与复发情况较少，值得推广。 　　[?P键词] 西咪替丁；叶酸；腹泻；临床效果 　　[中图分类号] R4 [文献标识码] A [文章编号] 1674-0742（2017）03（a）-0125-03 　　Study on Clinical Effect of Cimetidine and Folic Acid in Treatment of Diarrhea 　　GU Yu 　　Digestive System Department， Jilin Frontier Corps Hospital， Tonghua，Jilin Province，134000 China 　　[Abstract] Objective To observe the clinical effect of cimetidine and folic acid in treatment of diarrhea. Methods 78 cases of patients with diarrhea admitted and treated in our hospital from October 2014 to October 2016 were convenient selected and divided into two groups with 39 cases in each， the group A adopted the cimetidine and folic acid treatment， while the group B adopted the smeta and lactasin tablets treatment， and the clinical curative effect， symptom disappearance time and medication time， adverse reaction and recurrence conditions were compared between the two groups. Results The differences in the total treatment effective rate， symptom disappearance time and medication time， incidence rate of adverse reactions， recurrence rate after stopping taking drugs between the group A and the group B had statistical significance by comparison， （94.87%， 2.56%， 5.13% vs 82.05%， 10.26%， 25.64%）（P0.05）. Conclusion The curative effect of cimetidine and folic acid in treatment of diarrhea is definite with rapid symptom relief， short treatment time， few adverse reactions and recurrence situations， which is worth promotion. 　　[Key words] Cimetidine； Folic acid； Diarrhea； Clinical effect 　　腹泻是指每日排便次数显著多于正常频率，排便量≥200 g，且粪便呈水分较多、稀薄、脓血、有粘液等特点[1]。腹泻会导致肛门不适，甚至引