输卵管积水抽吸术在冻融胚胎移植中临床应用.docVIP

输卵管积水抽吸术在冻融胚胎移植中临床应用 　　【摘要】目的：探讨输卵管积水抽吸术在冻融胚胎移植（FET）中的临床应用。方法：对2011年9月至2013年6月我中心FET共742周期，其中积水抽吸组（A组）98周期，有积水但已在腹腔镜下行输卵管结扎或切除组（B组）114周期，有积水未抽吸组（C组）95周期，B超显示无积水组（D组）435周期，对各组FET患者的临床结局进行分析。结果：A、B、C、D组患者平均年龄，平均移植胚胎数等组间比较，P005，无统计学差异。四组着床率分别为3178%、3034%、2781%、3303%；流产率分别为222%、1336%、789%、521%；妊娠率分别为4592%、5175%、4000%、4851%，各组组间比较，P005，均无统计学差异。 结论：腹腔镜组妊娠率最高，无积水组次之，输卵管积水抽吸组妊娠率高于未抽吸组，提示输卵管积水抽吸术在患有输卵管积水但拒绝手术治疗患者FET前一天行抽吸术可取得一定疗效。 　　【关键词】输卵管积水；积水抽吸术；冻融胚胎移植；临床妊娠 　　【Abstract】Objectives： To discuss the clinical application of hydrosalpinx aspiration in frozen embryo transfer （FET）. Methods： A retrospective analysis was conducted in 742 cycles who undergoing FET with disease from Sep 2011 to Jun 2013. The patients were divided into four groups according to treatment for hydrosalpinx： taking out the tubal fluid （Group A， 98 cycles）， the tubal ligation or salpingectomy by laparoscope （Group B， 114 cycles）， without treatment of hydrosalpinx （Group C， 95 cycles）， the control group （Group D， 435 cycles）. The clinical outcome of each group of patients was analyzed. Result： The data revealed that there were no significant differences among four groups in the mean age of patients and the average number of transferred embryos. The FET implantation rates were 31.78%， 3034%， 27.81% and 33.03%， respectively in these four groups. The abortion rates and pregnancy rates of group A， group B， group C and group D were 2.22% and 45.92%， 13.36% and 51.75%， 789% and 4000%， and 5.21% and 48.51%， respectively， which showed no significant difference. Conclusions： The pregnancy rate of the laparoscopic group is the highest， followed by the control group， the hydrosalpinx aspiration group and aspiration group in sequence. From what has been discussed above， it is revealed that hydrosalpinx aspiration in the day before the FET on patients with hydrosalpinx but refused to surgery is helpful. 　　【Key words】Hydrosalpinx； A spiration； Frozen embryo transfer （FET）； Clinical preganancy rate 　　【中图分类号】R711.7