输尿管软镜治疗肾结石临床疗效及对肾功能影响作用.docVIP

输尿管软镜治疗肾结石临床疗效及对肾功能影响作用 　　[摘要] 目的 探?输尿管软镜治疗肾结石的临床疗效及对肾功能的影响作用。 方法 选择2016年2月～2017年1月76例肾结石患者，根据手术治疗方法分为两组，各38例。对照组采用传统碎石手术进行治疗，输尿管软镜组则采用输尿管软镜治疗。比较两组肾结石清除率；肾结石清除时间、手术过程丢失的血液量、术后平均住院天数；干预前后患者尿素氮水平、血肌酐水平、中性粒细胞明胶酶相关载脂蛋白；手术并发症发生率。 结果 输尿管软镜组肾结石清除率高于对照组（P0.05）；干预后输尿管软镜组尿素氮水平、血肌酐水平、中性粒细胞明胶酶相关载脂蛋白低于对照组（P0.05）。输尿管软镜组手术并发症发生率显著低于对照组（P0.05）。 结论 输尿管软镜治疗肾结石疗效确切，可提高结石清除率，减少手术创伤，减少术中出血和并发症，加速患者术后康复，缩短住院时间，且对肾功能的影响较小，值得推广。 　　[关键词] 输尿管软镜；肾结石；肾功能；并发症；结石清除率 　　[中图分类号] R692.4 [文献标识码] B [文章编号] 1673-9701（2017）29-0047-03 　　Clinical efficacy of flexible ureteroscope in the treatment of renal calculus and its eEffect on renal function 　　LUO Huaijing LIN Chaolu CHEN Jiande YE Feng XIAO Tan DONG Xingmo 　　Department of Urinary Surgery， Longyan First Hospital of Fujian Medical University， Longyan 364000， China 　　[Abstract] Objective To investigate the clinical effect of flexible ureteroscope in the treatment of renal calculi and its effect on renal function. Methods A total of 76 patients with renal calculi were collected from February 2016 to January 2017 and were assigned to groups according to the surgical methods， with 38 patients in each group. The control group was given traditional lithotripsy， and the flexible ureteroscopy group was given flexible ureteroscopy. The clearance rate of kidney stones； kidney stones removal time， the amount of blood loss during surgery， the average length of hospital stay after surgery； serum levels of urea nitrogen， serum creatinine levels， neutrophil gelatinase-related apolipoproteins before and after intervention； the incidence rate of surgical complications were compared between the two groups. Results The removal rate of kidney stones in flexible ureteroscope group was higher than that in control group（P0.05）. The level of serum urea nitrogen， serum creatinine level and neutrophil gelatinase-related apolipoprotein in the flexible ureteroscope group were lower than those in the control group after intervention （P 　　[Key words] Flexbile ureteroscope