降压药在老年高血压病患者中临床药学探析.docVIP

降压药在老年高血压病患者中临床药学探析 　　doi：10.3969/j.issn.1007-614x.2014.11.4 　　摘 要 目的：探讨老年高血压病患者采用降压药治疗的临床药学特点。方法：收治老年高血压患者100例，作为研究对象，分析降压药物应用特点。结果：临床高血压药物常用种类包括交感神经抑制剂、利尿剂、血管紧张素转换酶抑制剂、钙拮抗药、血管扩张药等。其中以缬沙坦使用率32%最高；呋噻米其次，使用率19%；硝苯地平使用率10%；卡托普利使用率5%；硝普钠使用率3%；利美尼定使用率2%等。就恢复率比较，卡托普利相对较低。不良反应相对均较高，未超过20%。结论：针对老年高血压患者选用降压药物治疗时，需对机体耐药性、高血压病情程度充分考虑，针对性用药，注意并发症防范，以提高治疗后的康复率，保障药物效果，避免不良事件发生，提高老年患者的生存质量。 　　关键词 降压药 老年 高血压 临床药学 探析 　　Analysis of clinical pharmacy of antihypertensive drugs in elderly patients with hypertension 　　Zhang Lingyu 　　Pharmacy Department，the Peoples Hospital of Bingchuan County，Dali State，Yunnan 671600 　　Abstract Objective：To explore the clinical pharmacy characteristics of antihypertensive drugs in the treatment of elderly patients with hypertension.Methods：100 elderly patients with hypertension were selected.Application characteristics of antihypertensive drugs were analyzed.Results：In clinical hypertension drugs，some species were commonly used，including sympathetic inhibitors，diuretics，angiotensin converting enzyme inhibitors，calcium antagonists，vasodilators and so on.Among them，the use rate of valsartan was the highest（32%）；the second was furosemide with the use rate of 19%；the use rate of nifedipine was 10%；the use rate of captopril was 5%；the use rate of sodium nitroprusside was 3%；the use rate of rilmenidine was 2%.For the comparison of recovery rate，captopril was relatively low.Adverse reactions were all relatively higher with less than 20%.Conclusion：When we choose antihypertensive drug therapy for elderly patients with hypertension，we should consider the drug resistance of the body and hypertension severity.We need to adopt the targeted drugs and pay attention to prevention of complications in order to improve the recovery rate，guarantee the drug effect，avoid adverse events and improve the quality of life of elderly patients. 　　Key words Antihypertensive drugs；Elderly；Hypertension；Clinical pharmacy；Analysis 　　近年来，随着我国人口结构步入老龄化进程加剧，加之饮食转变及生活压力的增加，高血压的发病