重组人脑利钠肽辅助介入术对急性心肌梗死合并心源性休克患者炎症因子影响.docVIP

重组人脑利钠肽辅助介入术对急性心肌梗死合并心源性休克患者炎症因子影响 　　【摘要】目的：探讨急性心肌梗死合并心源性休克患者采用重组人脑利钠肽辅助介入治疗的临床效果。方法：选择2016年10月-2018年5月商丘市第一人民医院急诊心内科收治的急性心肌梗死合并心源性休克患者60例，使用随机数表法将所有患者分为2组，各30例。对照组予以予以常规介入治疗，观察组在术前予以重组人脑利钠肽辅助治疗，比较两组患者炎症因子水平及心肌酶谱指标变化情况。结果：与对照组相比，治疗后观察组患者各炎症因子水平及心肌酶谱指标水平均较低，差异有统计学意义（P005）。结论：重组人脑利钠肽辅助介入治疗可对急性心肌梗死合并心源性休克患者正常心肌功能形成良好的保护作用，同时可降低机体炎症反应，有利于改善患者预后。 　　【关键词】急性心肌梗死；心源性休克；重组人脑利钠肽；炎症因子 　　【中图分类号】R54222 　　【文献标志码】B 　　【文章编号】1005-0019（2018）07-017-01 　　Effect of recombinant human brain natriuretic peptide Assisted Intervention on inflammatory factors in patients with acute myocardial infarction complicated by cardiogenic shock 　　Su Jiankang （Department of Cardiology， Department of Cardiology， Shangqiu First Peoples Hospital， Henan， Shangqiu， 476100）， CCU 　　Abstract Objective：To investigate the clinical effect of recombinant human brain natriuretic peptide （BNP） in patients with acute myocardial infarction complicated with cardiogenic shock. Methods： 60 patients with acute myocardial infarction combined with cardiogenic shock treated in the emergency department of Cardiology， Shangqiu First Peoples Hospital， October 2016 -2018， were divided into 2 groups， 30 cases each with random digital meter. The control group was given routine interventional therapy， and the observation group was treated with recombinant human brain natriuretic peptide before operation， and the level of inflammatory factors and the changes of myocardial enzyme spectrum index were compared between the two groups.Results： compared with the control group， the levels of inflammatory factors and myocardial enzyme spectrum index of the patients in the observation group were lower than those in the control group， and the difference was statistically significant （P005）. Conclusion： recombinant human brain natriuretic peptide assisted interventional therapy can protect the normal myocardial function of patients with acute myocardial infarction combined with cardiogenic shock， and can reduce the inflammatory respon