阿奇霉素联合红霉素序贯疗法治疗小儿支原体肺炎疗效观察.docVIP

阿奇霉素联合红霉素序贯疗法治疗小儿支原体肺炎疗效观察 　　【摘要】 目的 探究治疗支原体肺炎采用阿奇霉素联合红霉素序贯疗法的作用效果， 并分析其临床意义。方法 随机选取支原体肺炎患儿共60例， 采用抽签的方式， 将其分为对照组和观察组， 每组30例。其中， 对照组采用阿奇霉素对患儿进行治疗， 而观察组是在对照组的基础上加用红霉素联合治疗。记录两组患儿的治疗结果、平均退热时间、止咳时间以及住院时间。结果 观察组治疗的总体有效率96.67%明显高于对照组的73.33%， 同时观察组的平均退热时间、止咳时间以及住院时间也明显少于对照组， 差异均具有统计学意义（P0.05）。结论 对于支原体肺炎患儿， 采用阿奇霉素联合红霉素的序贯疗法进行治疗， 效果显著， 患儿能够在较短的时间内得以恢复， 值得临床推广应用。 　　【关键词】 支原体肺炎；红霉素；阿奇霉素；序贯疗法 　　DOI：10.14163/j.cnki.11-5547/r.2015.18.006 　　Curative effect observation of azithromycin combined with erythromycin in sequential therapy for pediatric mycoplasma pneumonia QIU Shao-zhen. Department of Pediatrics， Guangdong Zhongshan City Fusha Hospital， Zhongshan 528434， China 　　【Abstract】 Objective To investigate the effect by azithromycin combined with erythromycin in sequential therapy for pediatric mycoplasma pneumonia， and to analyze its clinical significance. Methods A total of 60 children with mycoplasma pneumonia were divided by draw lots into control group and observation group， with 30 cases in each group. The control group received azithromycin for treatment， and the observation group received additional erythromycin for treatment. Treatment outcomes， average fever subsidence time， cough relief time， and hospital stay of the two groups were recorded. Results The observation group had higher total effective rate as 96.67% than 73.33% of the control group， and its average fever subsidence time， cough relief time， and hospital stay were also shorter than the control group. The differences all had statistical significance （P0.05）. Conclusion Sequential therapy by azithromycin combined with erythromycin provides precise effect in treating mycoplasma pneumonia children， who have quick recovery in short time. This method is worthy of clinical promotion and application. 　　【Key words】 Mycoplasma pneumonia； Erythromycin； Azithromycin； Sequential therapy 　　随着现代化进程的不断推进， 我国工业的飞速发展， 一些疾病一直在威胁着人类的健康， 并呈现出较高的发病率， 例如肺炎。肺炎是儿科常见的呼吸道疾病， 其中支原体感染引起的肺炎近年呈上升趋势， 占总体肺炎的10%左右[1]， 有的地方甚至高达30%。临床