饮食指导对糖尿病高危足患者血清维生素A和维生素E水平影响.docVIP

饮食指导对糖尿病高危足患者血清维生素A和维生素E水平影响 　　[摘要] 目的 探讨饮食指导对糖尿病高危足患者血清维生素A和维生素E水平的影响。 方法 选择2013年10月～2015年10月中国中医科学院广安门医院门诊及住院治疗的糖尿病高危足患者100例为研究对象，按单盲随机法分为治疗组和对照组，每组各50例。均严格控制血糖、血压、血脂，治疗组在此基础上还给予严格的饮食指导，疗程为1个月。观察治疗前后两组患者空腹血糖（FPG）、胆固醇（CHO）、血脂（TG）、糖化血红蛋白（HbA1c）、踝肱指数（ABI）及维生素A、E水平的变化。 结果 治疗后，治疗组FPG、CHO、TG和HbA1c均较治疗前明显改善，差异均有高度统计学意义（P 0.01）；治疗后治疗组FPG水平明显低于对照组，差异有统计学意义（P 0.05）。治疗组治疗前后ABI比较，差异有统计学意义（P 0.05）。治疗后治疗组血清维生素A和维生素E含量均较治疗前明显改善，且高于对照组治疗后，差异均有高度统计学意义（P 0.01）。 结论 饮食指导可有效避免糖尿病高危足患者血清维生素A和维生素E的缺乏，有利于糖尿病高危足的预防和治疗。 　　[关键词] 糖尿病高危足；维生素A；维生素E；饮食指导 　　[中图分类号] R587.2 [文献标识码] A [文章编号] 1673-7210（2016）04（c）-0065-05 　　[Abstract] Objective To study influence of diet guide on the levels of serum vitamin A and E of patients with high risk diabetes foot. Methods 100 patients with high risk diabetes foot from October 2013 to October 2015 in Guanganmen Hospital， China Academy of Chinese Medical Sciences were collected and divided into treatment group and control group randomly， 50 cases in each group. Strict control of blood glucose， blood pressure， blood fat was carried among two groups， and strict diet guide were given to the treatment group for 1 month in addition. Levels of FPG， CHO， TG， HbA1c， ABI， and serum vitamin A and E were observed before and after treatment. Results Compared with before treatment， FPG， CHO， TG and HbA1c of the treatment group were significantly improved after treatment， the differences were statistically significant （P 0.01）； FPG of the treatment group after treatment was lower than that of the control group， the difference was statistically significant （P 0.05）. ABI of the treatment group was improved after treatment （P 0.05）. Levels of serum vitamin A and E of the treatment group were significantly improved after treatment， and were higher than those of the control group， the differences were statistically significant （P 0.01）. Conclusion Dietary guidance can avoid the deficiency of vitamin A and E of patients with high risk diabetes foot effectively， and d