高渗盐水雾化吸入在毛细支气管炎治疗中应用.docVIP

高渗盐水雾化吸入在毛细支气管炎治疗中应用 　　[摘要] 目的 探讨高渗盐水雾化吸入治疗毛细支气管炎的临床疗效。 方法 将92例毛细支气管炎患儿随机分为两组，每组46例，常规治疗基础上治疗组采用3.0%氯化钠溶液雾化吸入，对照组采用0.9%氯化钠溶液雾化吸入，比较两组患儿治疗后24 h、72 h Lowell评分，比较两组症状、体征缓解时间、住院时间及治疗总有效率，并比较治疗组不同病程患儿症状、体征缓解时间及住院时间。 结果 治疗前及治疗后24 h、72 h两组Lowell评分逐渐降低，治疗后72 h最低，治疗组低于对照组（P3 d组（P0.05）；治疗组总有效率高于对照组（P0.05）。 结论 高渗盐水雾化吸入治疗毛细支气管炎可尽快减少Lowell评分，缓解症状和体征，缩短住院时间，提高临床疗效，安全性好，在早期应用疗效更佳。 　　[关键词] 毛细支气管炎；高渗盐水；雾化吸入 　　[中图分类号] R725.6 [文献标识码] B [文章编号] 1673-9701（2015）04-0049-03 　　[Abstract] Objective To investigate the clinical effects of aerosol inhalation of hypertonic saline on bronchiolitis. Methods A total of 92 patients with bronchiolitis were randomly divided into two groups， with 46 cases in each group， the treatment group were treated with 3.0% Sodium Chloride Solution aerosol inhalation based on the conventional treatment， the control group were treated with 0.9% sodium chloride solution aerosol inhalation， compared the Lowell scores of the two groups at 72h and at 24h after treatment， compared symptoms and signs relieving time， hospitalization time and the total efficiency of the treatment， and compared symptoms and signs relieving time， and hospitalized time in various courses of disease of the treatment group. Results Lowell scores of the two groups at 24 h and at 72 h after treatment decreased， and lowest at 72h， the treatment group was lower than the control group （P3 d（P0.05）； The total effective rate of the treatment group was higher than that of the control group（P0.05）. Conclusion Aerosol inhalation of hypertonic saline on bronchiolitis can reduce the Lowell scores， relief of symptoms and signs， shorten the hospitalization time， improve the clinical efficacy， it has the advantage of safety， and the curative effect is better in the early application. 　　[Key words] Bronchiolitis； Hypertonic saline； Aerosol inhalation 　　毛细支气管炎是好发于冬春季节婴幼儿的下呼吸道感染性疾病，多发于2岁以下特别是1～6个月的婴儿，病原体主要为呼吸道合胞病毒，鼻病毒、腺病毒等病毒感染也可发病[1]。本病主要临床表现为咳嗽、气促和喘憋，严重者可发生呼吸困难。迅速缓解患儿的喘憋症状、改善缺氧状况、缩短病程是毛细支气管炎治疗的重点[2]，目前本病尚