ch9 Amino Acid Oxidation and The Production of Urea课件.ppt

Amino Acid Oxidation and the Production of Urea;Overview of the catabolism of amino acids in mammals;Contents;1. Degradation of proteins; The fraction of metabolic energy obtained from amino acids, whether they are derived form dietary or from tissue protein, varies greatly with the type of organism and with metabolic conditions. ;Dietary protein is enzymatically degraded to amino acids;Dietary protein ;Proteolytic enzymes (proteases) secreted by Pancreas; ;;NH3+—; 1. 载体转运：小肠，肌肉，肾小管细胞 ;2 γ-谷氨酰基循环：小肠，肾小管细胞，脑细胞;该循环分为两个阶段:;;Degradation of cellular proteins;Lysosomes deal primarily with;Prot