阿司匹林联合血塞通注射液对100例缺血性脑卒中患者血清Hcy水平的影响.docVIP

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阿司匹林联合血塞通注射液对100例缺血性脑卒中患者血清Hcy水平的影响.doc

阿司匹林联合血塞通注射液对100例缺血性脑卒中患者血清Hcy水平的影响   摘 要 目的:探讨阿司匹林联合血塞通注射液对缺血性脑卒中患者血清同型半胱氨酸(homocysteine,Hcy)水平的影响。方法:选取我院内一科住院部缺血性脑卒中患者200例,随机分为两组,对照组患者采用阿司匹林治疗,观察组在对照组的基础上采用血塞通注射液治疗,比较两组患者临床疗效与血清Hcy水平的差异。结果:观察组治疗有效率明显高于对照组(P0.05)。结论:阿司匹林联合血塞通注射液可通过多途径抗血小板聚集,抑制血栓形成,从而改善缺血性脑卒中患者的神经功能。   关键词 阿司匹林 血塞通注射液 缺血性脑卒中 同型半胱氨酸   中图分类号:R286; R743.33 文献标识码:A 文章编号:1006-1533(2016)13-0044-04   Effect of aspirin combined with Xuesaitong injection on the serum Hcy levels of 100 cases of patients with ischemic stroke*   WU Yujin(Division 1 of Internal Medical Department, Traditional Chinese Medicine Hospital of Meixian County,   Meizhou City, Meizhou 514000, China)   ABSTRACT Objective: To study the effect of aspirin combined with Xuesaitong injection on the serum homocysteine(Hcy) levels of patients with ischemic stroke. Methods: Two hundred cases of inpatients with ischemic stroke from our hospital were selected and randomly divided into a control group and an observation group with 100 cases each. The control group was treated by aspirin while the observation group were additionally treated by Xuesaitong injection besides aspirin. The clinical curative effect and serum Hcy levels were compared between two groups. Results: The efficient rate of the treatment was obviously higher in the observation group than in the control group (P0.05). Conclusion: Aspirin combined with Xuesaitong injection can inhibit the thrombosis by multi-channel antiplatelet aggregation and then improve neural function in patients with ischemic stroke.   KEY WORDS aspirin; Xuesaitong injection; ischemic stroke; Hcy   缺血性脑卒中是最为常见的脑卒中类型,占总脑卒中的60%~80%,其可能导致痴呆、失语与偏瘫,严重影响患者的生活质量,增加家庭与社会负担[1]。早期预防、诊断、治疗与康复是降低缺血性脑卒中患者死亡率与致残率的关键。脑血管循环障碍是导致缺血性脑卒中的重要原因,确保有效的脑灌注压力与脑血液循环是疾病治疗的重要原则[2]。缺血性脑卒中的治疗手段包括降低纤维蛋白原、抗血小板凝聚、溶解血栓、保护神经与血管内皮细胞、阻止缺血再灌注损伤,从而减轻脑组织缺损,减少脑梗死体积,促进神经功能恢复[3]。本院尝试采用阿司匹林联合血塞通注射液治疗缺血性脑卒中患者,取得显著的临床疗效,现报道如下。   1 资料与方法   1.1 临床资料   选取我院2014年1月―2015年6月期间内一科住院部缺血性脑卒中患者200例。纳入标准:全部患者均符合中华医学会全国第4次脑血管病学术会议修订的关于缺血性脑卒中的诊断标准,经颅脑

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