多索茶碱和氨茶碱治疗慢性阻塞性肺炎86例疗效对比研究.docVIP

多索茶碱和氨茶碱治疗慢性阻塞性肺炎86例疗效对比研究 　　[摘要] 目的 探讨在治疗慢性阻塞性肺炎过程中应用多索茶碱和氨茶碱的临床疗效。 方法 从2013年6月―2015年6月来该院治疗慢性阻塞性肺炎的患者当中选出86例，将患者随机分为两个小组，每组43例。对两组患者均采用常规治疗干预，其中一组在此基础上应用氨茶碱进行治疗，作为对比组；另外一组则在此基础上应用多索茶碱进行治疗，作为研究组。分别记录两组患者临床疗效和不良反应率。 结果 研究组患者治疗的总有效率为93.02%（40/43），明显高于对比组74.42%（32/43）；研究组患者治疗过程中的不良反应率为4.64%（2/43），明显低于对比组20.93%（9/43）。两组患者治疗数据存在较大，差异有统计学意义（P0.05）。 结论 在治疗慢性阻塞性肺炎时应用多索茶碱的临床疗效显著，并且不良反应率较低，能够保证患者治疗过程中和预后生活质量。 　　[关键词] 慢性阻塞性肺炎；多索茶碱；氨茶碱；临床疗效 　　[中图分类号] R563.1 [文献标识码] A [文章编号] 1674-0742（2016）02（a）-0129-02 　　Research on Comparison of Curative Effect of Doxofylline and Aminophylline in Treatment of 86 Cases with Chronic Obstructive Pneumonia 　　DU Hai-tao 　　Respiratory Medicine， Feicheng mining center hospital， Taian， Shandong Province， 271608 China 　　[Abstract] Objective To discuss the clinical curative effect of the application of doxofylline and aminophylline in treatment of chronic obstructive pneumonia. Methods 86 cases of patients with chronic obstructive pneumonia treated in our hospital from June 2013 to June 2015 were selected and randomly divided into two groups with 43 cases in each， the two groups were given conventional treatment intervention， the control group were treated with aminophylline on this basis， the research group were treated with doxofylline on this basis， the clinical curative effect and adverse reaction rate of the two groups were recorded. Results The total effective rate in the research group was obviously higher than that in the control group，93.02%（40/43）vs 74.42%（32/43）， the adverse reaction rate during treatment in the research group was obviously lower than that in the control group， 4.64%（2/43）vs 20.93%（9/43）， the treatment data of the two groups had a big difference with statistically significance （P0.05）. Conclusion The application of doxofylline in treatment of chronic obstructive pneumonia has an obvious clinical curative effect and a lower adverse reaction rate， which can guarantee the quality of life of patients during treatment and