乳酸菌合生元A肠内营养治疗重型颅脑外伤患者的疗效观察.docVIP

乳酸菌合生元A肠内营养治疗重型颅脑外伤患者的疗效观察 现代临床护理(M0demClicalNuraing)2010.9(5) 乳酸菌合生元A肠内营养治疗重型颅脑外伤患者的疗效观察 刘西韶,宁花兰,王佩琼,沈灿芳,魏晓芳 (深圳市宝安区人民医院,广东深圳,518101) [摘要】目的探讨乳酸菌合生元A肠内营养对重型颅脑外伤患者营养状态和免疫水平的影响.方法将75例患者随机分为肠 外营养(parenteralnutrition,PN)组,乳酸菌合生元A肠内营养(pefiopreativelyusingenteralnutritionwithfiber.containing,LEN)组,合生元B 肠内营养(enteralnuterlionwithfiber-containing,FEN)组,每组各25例,分别进行肠外营养,应用乳酸菌合生元A进行肠内营养,应用合 生元B进行肠内营养.比较3组患者营养支持前后各项营养指标的变化以及并发症的发生率.结果应用LEN进行肠内营养支持前 后,患者前白蛋白,淋巴细胞计数比较,差异无统计学意义(均Pgt;0.05);应用PN进行肠外营养,FEN进行肠内营养支持后.患者前白蛋 白,淋巴细胞计数低于营养支持前(均Plt;O.05).LEN与FEN组总并发症发生率比较,Pgt;0.05,差异无统计学意义:LEN,FEN组总并发 症发生率低于PN组(均Plt;O.05).结论应用乳酸菌合生元A进行肠内营养,可以促进患者蛋白质合成,免疫功能恢复,纠正负氮平 衡及减少并发症的发生. [关键词】乳酸菌;合生元;肠内营养;肠外营养;颅脑损伤 [中图分类号]R473.6[文献标识码]A[文章编号]1671—8283(2010)05-42048-03[DOI]10.3969/jJssn.167105.021 [Abstract]ObjectiveToprobeintothefeasibilityandeffectoftheenteralnutritionwithSpecificLactobacillusSynbiotiesin~vele headinjurypatients.MethodsThe75patientswererandomlydifidedintopaxenteralnutrition(PN)group,lacticacidbacteriasynbioticsA enteralnutrition(LEN)group,lacticacidbacteriasynbioticsBenteralnutrition(FEN)group,25P_,asesineachgroup,receivingparenteral nutrition,applicationoflacticacidbacteriasynbioticsAenteralnutrition,theapplicationoflacticacidbacteriasynbioticsB,respectively,for enteralnutrition.ChangesinnutritionalindicatorsandtheincidenceofcomplicationsbeforeandafternutritionMsupportweJtecomparedbetween threegroups.ResultsNosignificantdifferencewasfoundinpre-albuminandlymphocytecountinLEN~Toupbeforeandafternutritional support(Pgt;O.05).Pre—albuminandlymphocytecountinPNgroupandFENgroupweresignificandylowerafternutritionalsuppo~(Plt;O.05). Doubleinfection,stressulcerincidenceanddeathrateinFENgroupwerelessthanthePNgroup(Plt;0.05).Theoccurltencorateof complicationinLENandFENgroupwashigherthanthatinPNgroup(Plt;0.05).ConclusionApplicationoflacticacidbacteriainpatients withsynbioticscaTIpromotetheproteinsynthesisandimmunefunctionrecovery.correctthenegativenitrogenbalanceandreducecomplications.