精神分裂症伴强迫症状和强迫症比较研究.docVIP

精神分裂症伴强迫症状和强迫症比较研究 　　【摘要】 目的 比较强迫症患者与精神分裂症伴强迫症状患者的强迫症状的临床 差异。方法 采用强迫症状评定量表(Y-B0CS)、Hamilton抑郁量表(HAMD)、 Hamilton焦虑量表(HAMA)、阳性症状与阴性症状量表(PANSS)，对56例强迫症患者和49例伴 有强迫症状的精神分裂症患者进行评定，比较分析二者的临床差异及治疗结果。结 果 强迫症组的Y-BOCS、HAMD、HAMA等总分明显高于的精神分裂症伴强迫症状组(P0.O1)；治疗后两组各量表分均有明显下降(P0.01)，但强迫症组的症状改善优于 精神分裂症伴强迫症状组（P0.05）。结论 强迫症 患者的强迫体验、抑郁、焦虑等较明显，对治疗的反应也更好，对精神分裂症伴强迫症状的 患者可联合用药。 　　【关键词】 精神分裂症；强迫症状；强迫症；汉密尔顿抑郁量表；汉密尔顿焦虑 量表 　　 　　Comparative Study on Schizophrenia with Obsessive-compulsive Symptoms and Obses s ive-compulsive Disorder. Cheng Wanliang, Xia Zhong, Song Chuanfu, et al . The 4th Peoples Hospital of Wuhu, Wuhu 241002, P.R.China 　　【Abstract】 Objective To compare the clinical features of schizophren ia with obsessive-compulsive symptoms and obsessive-compulsive disorder. Methods 49 case s of schizophrenia with obsessive-cornpulsive symptoms and 56 cases of obsessiv e -compulsive disorder wereassessed by Y-BOCS, Hamilton depression rating scale for depression(HAMD), Hamilton depression rating scale for anxiety(HAMA), positi ve and negative syndrome scale(PANSS), the clinical features and the response totreatment were compared between two groups. Results The scoreof Y-BOCS, HAMD,HAMA in obsessive-compulsive disorder group was respectively higher than thati n schizophrenia with obsessive-compulsive symptoms group(P0.01). After treatment, the total score of each scale reduced significantly in both gro ups(P0.01), b ut obsessive-compulsive disorder group showed more improvement than schizophren i a with obsessive-compulsive symptoms group(P0.05). ConclusionObsessive-compul sive experience, depression, anxiety are marked in patients with obsessive-comp u lsive disorder, who are better responsive to treatment, combination therapy is n ecessary for schizophrenia with obsessive-compulsive symptoms. 　　【Key words】 Schizophrenia; Obsessive-compulsive symptoms; Obsessive-c ompulsive disorder; HAMD; HAMA 　　 　　强迫症状常见于强迫症和精神分裂症，抗精神病药物引起的强迫症状也越来越多见，造成临 床诊断与治疗的困难[1-4]。2004年以来，我们收集到49例精神分裂症患者伴有强 迫症