甲状腺功能减退和妊娠期高血压疾病相关性探讨.docVIP

甲状腺功能减退和妊娠期高血压疾病相关性探讨 　　摘要：目的 分析探讨妊娠期高血压疾病与甲状腺功能减退之间的临床相关性。方法 分析于我院治疗的128例孕产妇，将其分为观察组（合并甲状腺功能减退）65例与对照组（不合并甲状腺功能减退）63例。测定孕产妇FT3、FT4、TSH水平，以及各组妊娠结局、新生儿出生后一般情况、出现并发症情况。结果 观察组孕产妇FT3、FT4水平低于对照组，TSH水平高于对照组，两组间比较差异具有统计学意义（P0.05）；观察组孕产妇出现高血压的概率明显高于对照组，差异具有统计学意义（P0.05）；对照组孕产妇终止妊娠天数晚于观察组，新生儿体重高于观察组，差异具有统计学意义（P0.05）。结论 妊娠期甲状腺功能减退是诱出现妊娠高血压的危险因素之一，对孕产妇的妊娠结局、新生儿的出生时的一般情况具有较大影响，临床中应积极处理以改善孕产妇的妊娠结局。 　　关键词：妊娠期高血压；甲状腺功能减退；妊娠结局；相关性探讨 　　Correlation Analysis of Hypertensive Disorder Complicating Pregnancy and Hypothyroidism 　　LI Jian-feng 　　（Department of Obstetrics and Gynecology，Chengjiang County Peoples Hospital，Yuxi 652599，Yunnan，China） 　　Abstract：Objective To analysis the relationship between pregnancy induced hypertension and hypothyroidism.Methods 128 cases of pregnant women treated in our hospital were divided into the observation group （with hypothyroidism） in 65 cases and the control group（no complicated with hypothyroidism） in 63 cases.Tested the FT3，FT4，TSH levels，and the outcome of pregnancy，after the birth of the general situation，complications.Results The observation group FT3，FT4lower than the control group，the TSH was higher than that in the control group；observation group maternal hypertension appear probability is significantly higher than the control group；the control group the observation group days later than maternal termination of pregnancy，neonatal the body weight was higher than the observation group，with significant difference（P0.05）.Conclusion Gestational thyroid dysfunction is one of the risk factors of hypertension of pregnancy induced，which has a great influence in general birth outcome of pregnancy on maternal and newborn 　　Key words：Pregnancy induced hypertension；Hypothyroidism；Pregnancy outcome；Correlation 　　甲状腺疾病是一种较常见的内分泌系统疾病，尤以育龄期女性在孕期较为多见。研究发现[1]，妊娠合并甲状腺功能减退对孕妇及胎儿会产生较大影响。不仅增加了孕产妇在孕期出现贫血、高血压、糖代谢异常等疾病的概率，甚至可诱发孕产妇出现流产、早产、死胎等。甲状腺功能减退者易出现高血压，而妊娠期高血压综合征为仅次于产科出血的第二位孕产妇致死原因[2]，因此临床中应积极寻找对应措施，以降低相关原因引起的母婴高死亡率。虽然近年来我国对该病逐渐重视，但孕妇甲状腺功能对子代的发育影响机制至今尚不清楚