97例酚妥拉明联合呋塞米治疗顽固性心力衰竭临床的研究.docVIP

97例酚妥拉明联合呋塞米治疗顽固性心力衰竭临床的研究 　　[摘要] 目的:探讨酚妥拉明联合呋塞米在顽固性心力衰竭治疗中的效果,以为其治疗提供依据。方法:选取2007年11月～2009年12月于我院进行治疗的97例顽固性心力衰竭患者为研究对象,将其随机分为对照组(酚妥拉明组)47例和观察组(酚妥拉明联合呋塞米组)50例,并将两组患者的治疗效果及副作用发生率等进行比较分析。结果:经治疗后,发现观察组的治疗效果明显好于对照组,有显著性差异(P0.05)。结论:在顽固性心力衰竭的治疗中,采用酚妥拉明联合呋塞米的治疗方法效果好,且较为安全,值得临床进一步研究。 　　[关键词] 顽固性心力衰竭;酚妥拉明;呋塞米;研究 　　[中图分类号]R541.6 [文献标识码]B [文章编号]1673-7210(2010)05(b)-050-02 　　 　　The clinical study of Phentolamine combined with Furosemide in the patients with refractory heart failure 　　GUO Ping1, DU Yaoxin2 　　(1.Forestry Industry General Hospital of Heilongjiang Province,Harbin 150040, China; 2.Xilin Hospital of Xilin Area, Yichun City, Heilongjiang Province,Yichun 153025, China) 　　[Abstract] Objective: To study the effect of Phentolamine combined with Furosemide in the patients with refractory heart failure in order to provide evidence for the treatment. Methods: 97 cases patients with refractory heart failure in our hospital from November 2007 to December 2009 were selected as research object,then were divided into control group (phentolamine group) 47 cases and observation group (phentolamine combined with furosemide group) 50 cases. Then the effect and incidence of side effects of the two groups were analyzed, and the results were compared. Results: The effect of observation group were better than that of control group, there were significant differences (P0.05). Conclusion: The effect of Phentolamine combined with Furosemide in the patients with refractory heart failure is better,safety,and worthy of further study. 　　[Key words] Refractory heart failure; Phentolamine; Furosemide; Study 　　 　　本研究中,笔者选取97例顽固性心力衰竭患者为研究对象,对其采用不同的治疗方案进行治疗,后将效果进行研究比较,具体结果及经验总结报道如下: 　　1资料与方法 　　1.1 一般资料 　　选取2007年11月～2009年12月于我院进行治疗的97例顽固性心力衰竭患者为研究对象,将其随机分为对照组(酚妥拉明组)47例和观察组(酚妥拉明联合呋塞米组)50例。对照组的47例患者中,男27例,女20例,年龄50～77岁,NYHA心功能分级[1]:Ⅱ级15例,Ⅲ 19例,Ⅳ级 13例。观察组的50例患者中,男29例,女21例,年龄52～78岁,NYHA心功能分级:Ⅱ级16例,Ⅲ20例,Ⅳ级14例。两组患者在年龄、性别及心功能分级等基本情况方面进行比较,均无显著性差异(均P0.05),具有可比性。 　　1.2方法 　　对照组在常规治疗的基础上加用酚妥拉