不同产地薄荷药材商品质量及差异的研究.docVIP

不同产地薄荷药材商品质量及差异的研究 　　[摘要] 该文利用气相色谱质谱联用（GCMS）分析了薄荷药材挥发油的化学成分，并结合气相色谱法（GC）对7个挥发性成分进行含量测定，以比较传统道地产区江苏、当今主产区安徽及其他产区薄荷药材挥发性成分之间的差异。实验结果显示：收集的薄荷药材挥发油分为4种化学型：①薄荷醇薄荷酮型、②胡薄荷酮薄荷酮型、③胡椒酮薄荷醇型、④氧化胡椒酮型；薄荷醇?樗?有薄荷样品挥发性成分中含量最高的成分；安徽与其他产区薄荷挥发油成分之间的差异相对明显，江苏产区薄荷与另两个产区则存在交叉性。该文研究了不同产地薄荷药材挥发油的主要成分及产地间的差异，建立了薄荷药材多个挥发性成分的含量测定方法，为薄荷药材质量标准的提高提供了基础。 　　[关键词] 薄荷； 产地； 挥发性成分； 定性分析； 定量分析 　　Analysis on quality and differences of Mentha haplocalyx from different regions 　　XU Yiming1， YUE Wei1， SANG Mengru1， WU Dawei1， LIU Chanchan1， ZHAO Lingling1， WU Qinan1，2，3* 　　（1. College of Pharmacy， Nanjing University of Chinese Medicine， Nanjing 210023， China； 　　2. Collaborative Innovation Center of Chinese Medicinal Resources Industrialization， Nanjing 210023， China； 　　3. National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and 　　Formulae Innovative Medicine， Nanjing 210023， China） 　　[Abstract] A gas chromatographymass spectrometry（GCMS）method was established for the analysis of volatile components in Mentha haplocalyx， and seven principal components were quantified by gas chromatography（GC）. Based on these analyses， the differences of volatile components in M. haplocalyx from Jiangsu， Anhui and other regions were compared. The results showed that the volatile oil of M. haplocalyx was divided into four chemical types：mentholmenthone type， pulegonementhone type， piperitonementhol type， piperitone epoxide type， and mentholmenthone type was the principal type. Menthol was the highest and pulegone was the lowest. The differences of M. haplocalyx from Anhui and other regions were obvious. The major volatile components and the differences of M. haplocalyx from different regions were confirmed and a quantitative method was established for the determination of volatile components， which provided the basis for improving the quality standard of M. haplocalyx. 　　[Key words] Mentha haplocalyx； different regions； volatile components； qualitative analysis； quanti