七叶皂苷钠联合甘露醇治疗脑出血临床疗效的探讨.docVIP

七叶皂苷钠联合甘露醇治疗脑出血临床疗效的探讨 　　【摘要】 目的 分析七?~皂苷钠联合甘露醇治疗脑出血的临床疗效。方法 86例脑出血患者， 随机分为观察组与对照组， 各43例。两组除了给予常规的基础治疗外， 对照组给予甘露醇静脉滴注， 观察组在对照组的基础上给予七叶皂苷钠静脉滴注， 比较两组患者临床疗效、治疗前后神经功能缺损评分、血肿量以及不良反应情况。结果 治疗后， 观察组患者临床治疗总有效率为95.3%， 明显高于对照组的69.8%， 差异具有统计学意义（P0.05）；治疗后， 观察组患者神经功能缺损评分及血肿量均明显低于对照组， 差异具有统计学意义（P0.05）。结论 给予脑出血患者七叶皂苷钠联合甘露醇治疗， 对于改善患者的预后具有明显的意义。 　　【关键词】 脑出血；七叶皂苷钠；甘露醇 　　DOI：10.14163/j.cnki.11-5547/r.2017.32.051 　　Discussion on clinical efficacy of sodium aescinate combined with mannitol in the treatment of cerebral hemorrhage FU De-an， WANG Xu， WEI Liang， et al. Department of Internal Medicine-Neurology， Chongqing City Kaizhou District People’s Hospital， Chongqing 405400， China 　　【Abstract】 Objective To analyze the clinical efficacy of sodium aescinate combined with mannitol in the treatment of cerebral hemorrhage. Methods A total of 86 cerebral hemorrhage patients were randomly divided into observation group and control group， with 43 cases in each group. Both groups received conventional basic treatment， and the control group also received intravenous infusion of mannitol. The observation group received intravenous infusion of sodium aescinate on the basis of the control group. Comparison were made on clinical efficacy， neurological deficit score before and after treatment， hematoma volume and adverse reactions between two groups. Results After treatment， the observation group had obviously higher total effective rate of clinical treatment as 95.3% than 69.8% in the control group， and the difference was statistically significant （P0.05）. After treatment， the observation group had obviously lower neurological deficit score and hematoma volume than the control group， and the difference was statistically significant （P0.05）. Conclusion Combination of sodium aescinate and mannitol shows obvious significance in improving prognosis of patients with cerebral hemorrhage. 　　【Key words】 Cerebral hemorrhage； Sodium aescinate； Mannitol 　　脑出血是一种比较常见的急性脑血管疾病， 中老年人群为高发的人群。脑出血后血肿会压迫脑组织， 患者