virology15tumorvir ppt课件资料讲解.pptVIP

Oncogenic Viruses;Cell cycle control proteins;Tumor suppressor Rb;Tumor suppressor p53;Oncogenic viruses may be RNA or DNA;Viruses cannot kill cell to be tumorigenic;RNA transforming viruses are retroviruses so far… (hepC);oncogenes;Constitutive - agonist independent receptors;V-onc genes - transducing ;Cis-acting insertions are low efficiency tumor viruses;;Identifying c-onc in mouse tumors;Hepatitis B;DNA transforming viruses can be found in all families;How are cells transformed?;How should these proteins be similar?;Amino acid sequence similarities in Rb binding site;HPV E7 sequences diffe