子宫内膜息肉不孕患者行宫腔镜治疗后自然妊娠相关因素的研究.docVIP

子宫内膜息肉不孕患者行宫腔镜治疗后自然妊娠相关因素的研究 　　【摘要】目的：探讨子宫内膜息肉不孕患者行宫腔镜治疗后的自然妊娠状况。方法：回顾性分析宫腔镜手术治疗的76例子宫内膜息肉合并不孕症患者的临床资料，并随访其自然妊娠状况。结果：76例患者中术后18个月内自然妊娠51例，自然妊娠率为67.11%，其中术后6个月内自然妊娠率为84.31%；术后妊娠组年龄明显低于未妊娠组，差异有统计学意义（P0.05）。结论 对于无其他原因引起不孕的子宫内膜息肉患者来说，宫腔镜治疗可以明显提高患者术后自然妊娠率，年龄越小则术后自然妊娠的成功率越高，且术后6个月是妊娠的最佳时间。 　　【关键词】 子宫内膜息肉；宫腔镜；妊娠；因素 　　Study on natural pregnancy status of endometrial polyps patients with infertility after hysteroscopic treatmentWANG Yanming1， HU Gaiqin2， LI Xiaolin1. 1.Department of Gynecology， TheHospital Affiliated to Yan’an University， Yan’an 716000， China； 2.Department of Obstetrics， The Hospital Affiliated to Yan’an University， Yan’an 716000， China 　　【Abstract】Objectives： To investigate the natural pregnancy status of endometrial polyps patients with infertility after hysteroscopic treatment. Methods： Clinical data of 76 endometrial polyps patients with infertility treated by hysteroscopy was retrospectively studied and the patients were followed up on natural pregnancy status. Results： among 76 patients， there were 51 people with naturally pregnant within 18 months after surgery. The natural pregnancy rate was 67.11% and that was 84.31% within 6 months after surgery； the age in pregnancy group was significantly lower than that in the non-pregnant group and the difference was statistically significant （P0.05）. Conclusions： For endometrial polyps patients with infertility， hysteroscopic treatment can significantly improve postoperative natural pregnancy rate. The younger patients are， the more success rates after surgery will be achieved. The best time for pregnancy is within six months after the surgery. 　　【Key words】Endometrial polyps； Hysteroscopy； Pregnancy； Factor 　　【中图分类号】R737.33【文献标志码】A 　　子宫内膜息肉（endometrial polyps， EP）是妇女最常见的子宫内膜良性病变之一，是一种突出于子宫内膜表面的良性结节，由子宫内膜腺体以及纤维化子宫内膜间质（含有厚壁血管）构成[1]。临床上可出现生育年龄月经间期出血、月经过多甚至可引起不孕，绝经后则以不规则出血为主[2]。子宫内膜息肉影响引起妇女不孕的机制目前尚未完全明确，一般认为可能与子宫内膜息肉对精子运送、胚胎植入或抑制因子的影响有关[3，4]。宫腔镜手术目前已经广泛应用于子宫内膜息肉的治疗[5]。本研究通过回顾性分析宫腔镜手术治疗的76例子宫内膜息肉合并不孕症患者的临床