威海市区肥胖中小学生代谢紊乱的的特点调查分析.docVIP

威海市区肥胖中小学生代谢紊乱的的特点调查分析 　　【中图分类号】R589.2【文献标识码】A【文章编号】1005-2720(2009)05-0148-03 　　【摘要】目的：了解威海市区肥胖中小学生代谢紊乱的特点，为肥胖的干预提供依据。方法：对100名肥胖和100名对照组学生进行BMI、腰围、血糖、胰岛素、血脂及尿酸水平检查，并分析各指标与体重、年龄、性别的关系。结果：肥胖组学生MS的检出率为22%。肥胖组学生的腰围、血压、空腹血糖、空腹胰岛素、尿酸及血脂(TC、TG、LDL-C)水平均高于对照组，HDL-C较对照组低，差异有统计学意义。肥胖学生中，代谢异常的检出率随着肥胖程度的增加而上升。结论：肥胖学生存在明显的代谢紊乱，高胰岛素血症普遍，高尿酸血症突出，同时存在高血压及血脂紊乱。 　　【关键词】肥胖；学生；代谢紊乱；病例对照研究 　　 　　Characteristics of Metabolic disorder in Obese Students of Weihai and Yantai City.Xu Chao1，Xu Jinhua2，Tang Yi1，et al.(1The medical college of Qingdao university affiliated Weihai hospital，Shandong 264200 China；2Binzhou medical college Yantai area) 　　【Abstract】Objective：To explore the characteristics of metabolic disorder in obese students of weihai and yantai city and to provide evidence for prevention of obesity and metabolic syndrome (MS).Methods：100 normal-weight and 100 obese students aged 7~18 years old were selected from middle and primary schools in weihai and yantai.Height，weight，waist circumference (WC) and blood pressure were measured.Fasting venous blood was collected to evaluate blood uric acid，glucose，TG，TC，HDL，LDL and insulin levels.Results：The incidence of MS was 22% in obese students.There were significant differences at the levels of components of MS (SBp，DBp，WC，LDL-C，TG，TC，HDL-C，FPG，FINS，UA) among normal-weight and obese students.In obese students，the prevalence of abnormal metabolic disorder increased with body weight.Conclusion：Compared with normal-weight children，obese children have hyperinsulinemia，hyperuricemia and abnormal lipids and blood pressure.Examination of MS components should be strengthened to prevent obesity and reduce MS. 　　【Key Words】Obesity；Students；Metabolic disorder；Case-control studies 　　 　　中小学生作为一个特殊群体，正处于生理、心理迅速发育的关键时期。在众多传染病和严重营养不良性疾病得到基本控制后，单纯性肥胖成为目前影响中小学生健康的一个全球性的、重要的问题。国外学者曾指出：肥胖儿童的代谢紊乱危险增加，包括糖耐量受损(IGT)、胰岛素抵抗(IR)、糖尿病等[1]。为了解威海市区肥胖学生代谢紊乱特点，笔者采用病例对照研究，对该地区学生代谢综合征各成分水平进行了调查分析，为干预肥胖提供依据，以促进对中小学生肥胖症的研究和防治，对增强青少年体质、预防成年期疾病有着非常重要的意义。 　　 　　1 资料与方法