二维应变超声心动图评价高血压左室心肌舒张期应变率的初步分析-影像医学与核医学专业论文.docxVIP

Results: In the whole HT group, left ventricular remodeling parameters were higher than control group. There was no significant difference in LVEF between two groups [(64.05 ± 4.93)% vs (63.52 ± 6.05)%, p 0.05] . There was a small decrease in left ventricular longitudinal systolic velocity (Sa) (p 0.05). The diastolic Ea decreased and E/Ea increased (p 0.01). 2DSE measurements showed that LV global systolic longitudinal strain rate (SrLs), early diastolic longitudinal strain rate (SrLE) and circumferential strain rate (SrCE) were decreased (p 0.05) in HT group, and there was an association between SrLE and LVMI and total wall thickness（r, -0.47 to -0.52， p 0.01）. The association between SrLs and SrLE was found ( r=0.38, p 0.01). LV global early diastolic strain rate (SrLE, SrCE, SrRE) decreased in the LVH group (p 0.05), which was not different in NLVH group (p 0.05). The analysis of left ventricular diastolic different segments strain rate showed that the basal segment and middle segment of early diastolic longitudinal strain rate (SrLMV 、 SrLPM) decreased (p 0.05) in NLVH group . Conclusions: 2-dimensional strain echocardiography detected the decrease in left ventricular systolic and early diastolic strain rate in hypertensive patients with normal LVEF. As for the left ventricular early diastolic strain rate, the longitudinal strain rate was decreased in the early stage of the left ventricular remodeling of hypertension, and the longitudinal, circumferential and radial strain rate were all decreased in hypertrophy stage. Key words: echocardiography/hypertension/left ventricular hypertrophy /ventricular function/speckle tracking imaging 英文缩略词 英文缩写 英文全称 中文全称 2DSE 2-Dimensional strain echocardiography 二维应变超声心动图 TDI Tissue doppler imaging 组织多普勒成像 SRI Strain rate imaging 应变率成像 HT Primary hypertension 原发性高血压 LVH Left ventricular hypertrophy 左室肥厚组 NLVH Non-left ventricular hypertrophy 左室非肥厚组 NC Normal control 正常对照 LVEDV Left ventricular end-diastolic volume 左室舒