生化2018 c16 rna transcription2教学材料.ppt

Class and functions of TF II Class Functions TF II A To stabilize the combination of TF II B and TBP to promoter TF II B To bind with TBP and serve as a bridge between other factors and pol II TF II D(TBP) To recognize specifically and to bind with TATA box TF II E To recruit TF II H, it has ATPase and helicase activity TF II F To bind to TF II B, and Pol II to prevent the wrong binding of pol II with nonspecific DNA sequence TF II H Helicase activity * (A point for cutting and adding a tail ) Structures of gene in eukaryotes: Enhancer Modification site Real termination site AATAA TATA