尿激酶联合丹参注射液治疗脑血栓形成45例的的疗效观察.docVIP

尿激酶联合丹参注射液治疗脑血栓形成45例的的疗效观察 　　[摘要] 目的 探讨尿激酶联合丹参注射液治疗脑血栓形成的临床效果。 方法 选择本院脑血栓形成患者90例，随机分为观察组和对照组。观察组患者给予尿激酶溶栓治疗，同时给予丹参注射液，对照组患者给予丹参注射液。两组患者均给予常规治疗。评定两组神经功能缺损情况。 结果 治疗后观察组NIHSS评分显著低于对照组，差异有统计学意义（P 0.05）；观察组总有效率显著高于对照组，差异有统计学意义（P 0.05）。 结论 尿激酶联合丹参注射液能够显著改善脑血栓形成患者的神经功能，临床效果显著，值得借鉴。 　　[关键词] 脑血栓形成；尿激酶；丹参注射液；疗效观察 　　[中图分类号] R743.32 [文献标识码] A [文章编号] 1674-4721（2012）03（c）-0073-02 　　 　　Clinical observation of urokinase combined with salvia injection on 45 cases with cerebral thrombosis 　　WANG Tiancai LI Fengbo ZHAO Xiwei 　　First Brain Department, Nanshi Hospital of Nanyang City in Henan Province, Nanyang 473000, China 　　[Abstract] Objective To explore the clinical efficacy of cerebral thrombosis combined with salvia injection on cases with cerebral thrombosis. Mehtods Ninety-two cases with cerebral thrombosis were selected, and divided into observation group and control group. Urokinase thrombolysis and salvia injection were given to observation group, salvia injection was used to control group. The routine treatment was used to the two groups. Neurologic impairment was measured. Results The score of NIHSS in observation group after treatment was lower than that in control group, there was statistical difference (P 0.05); The total effective rate in observation group was higher than that in control group, there was statistical difference (P 0.05). Conclusion Urokinase combined with salvia injection can improve the nerve function of patients with cerebral thrombosis, the clinical efficacy is significant. 　　[Key words] Cerebral thrombosis; Urokinase; Salvia injection; Clinical observation 　　 　　缺血性脑血管疾病可分为超早期、急性期、坏死期、软化期和恢复期。在脑血栓形成的超早期应用尿激酶溶栓治疗的临床效果得到临床认可。本文观察尿激酶联合丹参注射液治疗脑血栓形成的急性期的临床效果，现报道如下： 　　1 资料与方法 　　1.1 一般资料 　　选择本院2009年9月～2011年9月脑血栓形成患者90例，以上患者诊断符合中国第四届脑血管病会议制定的缺血性脑血管病诊断标准[1]，同时经头颅CT检查排除脑出血患者，患者均为发病初期和急性期，发病时间小于24 h。同时排除伴有癫痫发作患者、近期有活动性出血患者、出血倾向患者、严重全身性疾病患者、收缩压大于180 mm Hg或者舒张压大于120 mm Hg的患者。将上述患者分为观察组和对照组。观察组45例，男27例，女18例，年龄最小48岁，最大75岁，平均（59.3±6.4）岁；对照组患者45例，男2