阿托伐他汀钙片治疗高脂血症的的疗效观察.docVIP

阿托伐他汀钙片治疗高脂血症的的疗效观察 　　【摘要】 目的：探讨阿托伐他汀钙片治疗高脂血症的疗效。方法：选取2014年4-10月在本院治疗的50例高脂血症患者，随机分成对照组和观察组，每组各25例。对照组患者给予苯扎贝特片口服治疗，观察组给予阿托伐他汀钙片口服治疗。结果：两组治疗前的血脂指标比较差异无统计学意义（P0.05）；治疗4周后，与同组治疗前比较，两组患者的血脂指标差异有统计学意义（P0.05）；治疗8周后，两组比较差异均有统计学意义（P0.05）；治疗4周后，与同组治疗前比较，两组患者的颈动脉内膜中层厚度、斑块面积差异均有统计学意义（P0.05）；治疗8周后，两组比较差异均有统计学意义（P0.05），且观察组的治疗效果优于对照组。观察组不良反应发生率低于对照组，差异有统计学意义（P0.05）。结论：采用阿托伐他汀钙片治疗高脂血症能够取得满意的效果，并且安全可靠，值得临床推广使用。 　　【关键词】 阿托伐他汀钙片； 高脂血症； 疗效观察 　　The Curative Effect Detection of Treatment Hyperlipidemia by Atorvastatin Calcium Tablets/ZHAO Zhen.//Medical Innovation of China，2015，12（18）：136-138 　　【Abstract】 Objective：To approach curative effect detection of treatment hyperlipidemia by Atorvastatin calcium tablets.Method：50 patients with hyperlipidemia were selected in our hospital from April 2014 to Octomber 2014，which was to be divided into control group and detection group，25 cases in each group.The control group was treated by peroral Bezafibrate tablets，detection group was treated by peroral Atorvastatin calcium tablets.Result：Before treatment，compared the blood lipid indicators of two groups，the difference was no statistically significant（P0.05）.After 4 weeks of treatment，compared with the same group before treatment，the difference was statistically significant（P0.05）.After 8 weeks of treatment，compared between the two groups，the difference was statistically significant（P0.05）.After treatment 4 weeks，the between the two groups compared with before treatment，carotid intima-media thickness and plaque area of patients were obviously statistical differences（P0.05）.After treatment 8 weeks，compared the two groups had statistical difference（P 　　【Key words】 Atorvastatin calcium tablets； Hyperlipidemia； Curative effect detection 　　First-author’s address：Nanning Xiehe Hospital，Nanning 530031，China 　　doi：10.3969/j.issn.1674-4985.2015.18.052 　　随着我国人民生活水平和社会竞争压力水平的逐年增高，近年来，高血压、高血脂、高血糖以及冠心病等疾病的发病率也呈现逐年上升趋势，而且逐渐出现年轻化。这些疾病的发生严重影响了人民的生活质量，也威胁着人们的生命安全，因此对于三高症及冠心病的治疗刻不容缓[1-2]。高脂血症指的是血脂代谢发生异常