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than those in the model group. The differences of the area and the thickness of
mesolamella were not significant statistically in each group(P 0.05), which can
be shown by analysis of measurable indexes of vascular morphology. The area and
the thickness of intima, the proliferous ratio of intimal area and thickness, the ratio
of area of intima/mesolamella, the ratio of thickness of intima/mesolamella in the
model group were higher than those of sham-operated group(P 0.01). But All the
above indexes in alkaloid, glycoside, BHD, PNS and atorvatatin group were less
than those in the model group(P 0.01~ P 0.05).
Comparison of PCNA expression in different groups: the expression of PCNA in
the model group increased significantly compared with the sham group(P0.01).
The expressions of PCNA in alkaloid, glycosid, PNS and atorvatatin groups were
higher than those of the sham group(P 0.01~ P 0.05), but still lower than those
of the model group(P 0.01). While the expression of PCNA in BHD group was
higher than that of the sham group(P 0.01), the differences between BHD group
and model group were no significant statistically (P 0.05).
Comparison of cyclinD1 and cyclinE expressions in different groups: the
expression of cyclinD in the model groups was higher markedly than that of sham
1
group(P 0.01), while the expressions of cyclinD1 in alkaloid, glycosid, BHD,
PNS and atorvatatin groups were lower than those of the model group(P 0.01~P
0.05). The differences of cyclinE expressions between the model group and the
sham group were significant statistically (P0.01). The expressions of cyclinE in
alkaloid, glycosid and PNS groups were lower than those of model group (P
0.01~P 0.05). Although the expressions of cyclinE in BHD, atorvatatin groups
were lower than those of model group, the differences among them
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