卡托普利治疗心力衰竭120例临床剖析.docVIP

卡托普利治疗心力衰竭120例临床剖析 　　【摘要】 目的：观察分析卡托普利治疗心力衰竭的临床疗效。方法：从本院收治入院的心力衰竭患者中抽取120例，随机分为观察组与对照组，对照组患者实施常规抗心衰治疗，观察组患者在此基础上加用卡托普利治疗，观察两组患者的治疗效果。结果：观察组患者治疗总有效率明显高于对照组，治疗4个月后左室舒张、收缩末期内径减少程度和射血分数明显优于对照组，比较差异有统计学意义（P0.05）。结论：卡托普利可以有效改善心力衰竭患者左心室舒张、收缩末期内径及射血分数，明显提高对心力衰竭患者的临床治疗效果，具有在临床上进一步推广应用的价值。 　　【关键词】 卡托普利； 心力衰竭； 抗心衰治疗； 临床效果 　　Clinical Analysis on the Effect of Captopril for 120 Heart Failure Patients/LIU Hai-mei，LIU Xiu-ying.//Medical Innovation of China，2013，10（15）：123-125 　　【Abstract】 Objective： To observe the clinical efficacy of captopril in the treatment of heart failure analysis. Method： To select 120 patients with heart failure from our hospital， who were randomly divided into observation group and control group. The control group implemented routine anti heart failure treatment， and the observation group was treated with captopril on this foundation. To observe the therapeutic effect of the two groups. Result： The observation group’s total effective rate of treatment was significantly higher than the control group’s. 4 months after the treatment， left ventricular diastolic， systolic diameter reduction degree， and ejection fraction of the observation group was significantly better than that of the control group， and the difference was statistically significant（P0.05）. Conclusion： Captopril can improve heart failure patients with left ventricular diastolic， systolic diameter， and ejection fraction， and significantly improve the clinical effect in the treatment of heart failure， and have further extending application value with clinically. 　　【Key words】 Captopril； Heart failure； Heart failure therapy； Clinical effect 　　First-author’s address： Dalian University Affiliated Zhongshan Hospital， Dalian 116001， China 　　doi：10.3969/j.issn.1674-4985.2013.15.065 　　心力衰竭是较为常见的心脏疾病终末期临床症状，多由于心脏疾病患者的血流动力学异常和神经内分泌体系经过一系列较为复杂的过程后所导致[1]。该病病情较为危重，在心脏病患者中的发病率、致死率均较高，临床上对该病较为重视，如不能有效的控制并缓解病情可对患者的生活质量造成极大影响，预后较差，甚至威胁患者生命[2]。目前多使用利尿剂和洋地黄等制剂对该病患者进行抗心衰治疗，其疗效不是十分理想[3]。因此笔者通过对本院部分心力衰竭患者加入卡托