超高效液相色谱-串联质谱法测定乳制品中10种青霉素类抗生素残留.PDF

6 4 Vol. 6 No. 4 2015 4 Journal of Food Safety and Quality Apr. , 2015  10 * 张 燕, 舒 平, 阚海勋, 赵浩军, 杨卫花, 王 坤, 张 蕾 (, 671000) 摘 要: 目的 10 - 方法 , , 0.22 μm , -( 0.1% 5 mmol/L ), C + 18 , 20 min 10 ; (ESI ), (MRM), 结果 0.1~20 μg/L , 10 , 0.999; 0.2 μg/kg~1.0 μg/kg, 1.0 μg/kg~5.0 μg/kg; 70.2%~108.2%, 15%结论 10 , 关键词: ; ; ; - Determination of 10 residual penicillin in dairy products by ultra high performance liquid chromatography-tandem mass spectrometry * ZHANG Yan , SHU Ping, KAN Hai-Xun, ZHAO Hao-Jun, YANG Wei-Hua, WANG Kun, ZHAGN Lei (Dali State Comprehensive Technical Inspection Center, Dali 671000, China) ABSTRACT: Objective To establish a method for simultaneous determination of 10 residual penicillin in dairy products by ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). Methods The sample was extracted with acetonitrile and degreased with saturated acetonitrile n-hexane and filtered through 0.22 μm millipore membrane. The filtrate was detected by ultra high performance liquid chromatography-tandem mass spectrometry, identified by electrospray io