青春期延迟56例临床剖析.docVIP

青春期延迟56例临床剖析 　　【摘 要】 目的:探讨青春期延迟的分型诊断和治疗方法。方法：采用化学发光法测定促卵泡刺激素（FSH）、黄体生成素（LH）、睾酮（T）、雌二醇（E2）、泌乳素（PRL），同时进行绒毛膜促性腺素（HCG）兴奋试验。并进行外周血染色体检查和B超检查睾丸、附睾、精索、前列腺、精囊腺。根据检查结果进行分型诊断和病因学诊断，治疗以缺什么补什么为原则。结果：本组病例共56例，其中高促性腺激素型6例（占10.71%），低促性腺激素型50例（占89.29%）。通过激素的补充治疗，第二性征和阴茎均能得到改善，但睾丸生长缓慢，低促性腺激素型部分患者能恢复生殖功能，本组病例中3例精子密度正常，其中1例妻子已怀孕。结论：青春期延迟通过分型诊断，并进行相应的内分泌补充治疗，第二性征和阴茎发育正常，低促性腺激素型患者尚能恢复生殖功能。 　　【关键词】 青春期延迟； 高促性腺激素型； 低促性腺激素型 　　 　　Clinical analysis of 56 cases of the delay of puberty 　　CHEN Lisheng, CHEN Yequan, WU Miao 　　Department of Androgy, Jianguo Androgy Hospital at Nanjing, Jiangsu Nanjing 210006, China 　　【Abstract】 Objectives: To study the type-diagnosis and treatments of the delay of puberty. Methods: Mensurate the amount of FSH,LH,T, E2,PRL through the chemiluminescence, together with the HCG stimulate test. We also analyze the chromosome of peripheral blood,and examine testicles, epididymis, varicosity, prostate, and seminal vesicle by B-ultrason. Carry on both the typing and pathogenic diagnosis due to the results of these examinations, sticking to the principle of supplying whatever is scanty. Results: Among the 56 cases, 6 cases are high gonadotropic hormone, occupying 10.71% of the whole test results; 50 cases are low gonadotropic hormone which occupy the 89.29%. By the hormone supplying treatment, the second character of gender and the penis can be both improved but with the low growing rate of testicles. Part of the low gonadotropic hormone patients recuperate the reproductive function. The sperm density of three cases become normal, one of whose wife is getting pregnancy currently. Conclusion: type-diagnosis of puberty delay together with relevant hormone supplying treatment, the second character of gender as well as the function of penis develop normally. Patients with low gonadotropic hormone could probably get a recuperation in reproductive function. 　　【Key words】 Delay of puberty; High gonadotropic hormone; Low gonadotropic hormone 　　 　　 青春期延迟是一种青春发育的异常，表现为青