降钙素原的检测和应用-SIFIC感染网.PDF

·专家论坛 · 降钙素原的检测和应用——《感染相关生物标志物 临床意义解读专家共识》解读 朱美英 曹鄂洪 * （解放军南京总医院呼吸与危重症医学科 江苏 210002 ） 摘 要 检测感染相关生物标志物可辅助诊断感染性疾病，并在指导抗生素的使用和判断患者的预后等方面发挥重 要作用。近期，中国医药教育协会感染疾病专业委员会发布的《感染相关生物标志物临床意义解读专家共识》客观、全 面地介绍了感染相关重要生物标志物。本文就该共识中有关降钙素原检测和应用的相关内容作进一步解读。 关键词 降钙素原 感染性疾病 检测方法 R446.112; R51 A 1006-1533(2018)01-0014-05 中图分类号 ： 文献标识码 ： 文章编号 ： Detection and application of procalcitonin — interpretation for Expert Consensus on Clinical Significance Interpretation of Infection-related Biomarkers * ZHU Meiying, CAO Ehong (Department of Respiratory and Critical Care Medicine, Nanjing General Hospital of PLA, Jiangsu 210002, China) ABSTRACT Detection of infection-related biomarkers can assist physicians to diagnose disease, so it plays an important role in determining infection type and patient’s prognosis and guiding the use of antibacterial agents. Recently, Expert Consensus on Clinical Significance Interpretation of Infection-related Biomarkers was issued by Infectious Disease Professional Committee of Chinese Medical Education Association, in which the important infection-related biomarkers were introduced objectively and comprehensively. The contents related to the detection and application of procalcitonin in this expert consensus were further interpreted in this article. KEY WORDS procalcitonin; infectious disease; detection methods 感染是临床上的常见病和多发病，可发生于人体任 目前，生物标志物已成为临床上鉴别感染、判断病 一部位，可能会导致患者多个器官的炎症和并发症如肺 情严重程度和患者预后的常用工具，如炎性反应细胞类 炎、脓毒症等，严重的感染甚至会危及生命。大多数感 的白细胞、炎性反应介质类的白介素 -6 和白介素 -8、炎 染只要诊断准确、治疗恰当都可在相对较短的时间内治