肺癌的表观扩散系数值与肿瘤细胞密度的关系及其诊断价值-影像医学与核医学专业论文.docxVIP

第三军医大学硕士学位论文 第三军医大学硕士学位论文 PAGE PAGE 10 缩略语表 英文简称 ADC 英文全称 apparent diffusion coefficient 中文全称 表观扩散系数 AUC the area under the ROC curve ROC 曲线下面积 CI confidence interval 可信区间 CT computed tomography 计算机断层扫描 DCE-CT dynamic contrast enhanced CT 动态对比增强 CT DCE-MR dynamic contrast enhanced MR 动态对比增强 MR DOR diagnostic odds ratio 诊断比数比 DWI diffusion-weighted imaging 扩散加权成像 EPI echo planar imaging 回波平面成像 fMRI functional magnetic resonance imaging 功能磁共振成像 FOV field of view 视野 FP false positive 假阳性 FN false negative 假阴性 meanADC mean apparent diffusion coefficient 平均表观扩散系数 minADC minimum apparent diffusion coefficient 最小表观扩散系数 MRI magnetic resonance imaging 核磁共振 NLR negative likelihood ratio 阴性似然比 NSCLC non-small cell lung canIer 非小细胞肺癌 PLR positive likelihood ratio 阳性似然比 PET positron emission tomograpy 正电子发射计算机断层扫描 QUADAS the quality assessment of diagnostic studies 诊断性研究的质量评价 R correlation coefficient 相关系数 ROC the receiver operator characteristic 受试者操作曲线 ROI region of iIterest 感兴趣区 SEN sensitivity 敏感度 SPE specificity 特异度 SPECT single photon emission computed tomography 单光子发射计算机断层扫描 T1WI T1-weighted imaging T1 加权像 T2WI T2-weighted imaging T2 加权像 TE echo time 回波时间 TR repetition time 弛豫时间 TP true positive 真阳性 TN true negative 真阴性 Relationship and Diagnostic value of Apparent Diffusion Coefficient and Tumor Cellularity in Lung Cancer Abstract The correlation between apparent diffusion coefficient value and tumor cellularity in patients: A meta-analysis Backgrounds and objective： Studies conducted in vitro and in animal models show that the ADC value is highly inversely correlated with tumor cellularity. However, these results are controversial in patient; some studies confirm a notable inverse correlation while others present negative or even inverse results. Therefore, we performed this meta-analysis to explore the correlation between the ADC value and tumor cellularity in patients with tumors. Methods： We searched medical and scientific literature databases for studies discussi